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Antide, also known as Iturelix, is a synthetic GnRH (LHRH) antagonist (purity ? 99.53%), manufactured under GMP standards. It effectively suppresses LH and FSH release—widely utilized in reproductive and prostate cancer research. Available for both wholesale and retail; for laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Antide (CAS 112568-12-4), also known as Iturelix, is a potent synthetic luteinizing hormone–releasing hormone (LHRH/GnRH) antagonist. By competitively inhibiting GnRH receptors in the pituitary gland, it suppresses the secretion of LH and FSH, thereby exerting strong anti-ovulatory effects while releasing negligible histamine—a notable advantage over earlier generations of GnRH antagonists.
This agent is widely used in reproductive biology and hormone-dependent cancer studies, including prostate cancer research. Manufactured under GMP conditions with purity of 99.53%, Antide ensures high-quality consistency for experimental protocols.
| Parameter | Details |
|---|---|
| Product Name | Antide (Iturelix) |
| Synonyms | Iturelix; Nal-Lys GnRH antagonist; D-21074; PPI-149; ORF 32541 |
| CAS No. | 112568-12-4 |
| Purity | ? 99.53% (GMP-grade) |
| Molecular Formula | C??H???ClN??O?? |
| Molecular Weight | Approx. 1591 Da |
| Appearance | White to off-white powder |
| Solubility | Soluble in DMSO; prepare fresh solutions to avoid degradation |
| Storage Conditions | Store at –20 °C; protect from light and moisture; prepared solutions stable at –80 °C up to 6 months |
| Manufacturing Standard | GMP-compliant |
| Applications | Reproductive research, hormone regulation, prostate cancer studies |
| Regulatory Status | For laboratory research use only |
Antide functions as a GnRH antagonist by binding to GnRH receptors in the pituitary, inhibiting LH and FSH secretion without causing the flare effect seen with agonists. Its high anti-ovulatory activity and minimal histamine release make it a powerful tool for studies of reproductive endocrinology, infertility models, and hormone-sensitive cancers such as prostate cancer.
Since Antide is for experimental use only, clinical safety data are limited. Preclinical studies suggest minimal histamine release compared to earlier GnRH antagonists. Researchers should follow laboratory safety protocols strictly.
This product is intended strictly for laboratory research use only. It is not approved for human or veterinary therapeutic use. Please adhere to institutional safety guidelines when handling.
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 64 × 36 × 64 厘米 |
Antide is used as a GnRH antagonist to study hormonal regulation, reproductive biology, and hormone-dependent cancers like prostate cancer.
Antide is produced with a purity of at least 99.53% under GMP-compliant standards.
It binds to GnRH receptors in the pituitary, suppressing LH and FSH release without triggering a hormonal surge (flare effect).
Antide is also known as Iturelix, Nal-Lys GnRH antagonist, D-21074, and PPI-149.
The approximate molecular weight of Antide is 1591 Da.
Store at –20 °C, protected from light and moisture. Solutions should be prepared fresh in DMSO, and stock aliquots stored at –80 °C for up to six months.
No, Antide is for laboratory research only and is not approved for therapeutic or clinical use.
Yes, Antide is available in both wholesale and retail quantities, with GMP documentation available upon request.
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