Atosiban Acetate – Purity 99.76% | GMP Factory

描述

Atosiban acetate (CAS 914453-95-5), also known as ORF-22164 or RWJ-22164 acetate, is a synthetic nonapeptide and competitive antagonist of oxytocin and vasopressin receptors. Widely utilized in preclinical models to study suppression of uterine contractions and mechanisms of preterm labor, it offers a stable, high-purity tool (99.76%) for reproductive and vascular research.

Product Specifications

Mechanism of Action & Research Applications

Atosiban acetate acts as a competitive antagonist at oxytocin and vasopressin receptors, inhibiting oxytocin-mediated inositol triphosphate signaling, reducing intracellular calcium, and suppressing uterine contractions. It’s commonly used in:

• Preclinical tocolytic models to delay preterm labor

• Investigating uterine contractility and receptor signaling

• Experimental studies in assisted reproduction and implantation

• Research on receptor-specific modulation in reproductive physiology

Side Effects (For Research Context Only)

In experimental models, Atosiban acetate may induce:

• Mild hypotension and vasodilation due to receptor blockade

• Transient gastrointestinal effects like nausea

• Modulated implantation rates in reproductive studies

• Dose-dependent impacts on placental blood flow in isolated models

These effects are useful for understanding uterine and vascular responses under controlled research conditions.

Disclaimer

This product is strictly for laboratory research use only and is not approved for human, veterinary, or clinical application.