Brolucizumab Injection (Beovu) 27.6mg/0.23ml – Factory low price wholesale

描述

Brolucizumab is a humanized single-chain antibody fragment (scFv) targeting vascular endothelial growth factor A (VEGF-A). It is used in ophthalmological research to study mechanisms of wet age-related macular degeneration (wet AMD) and retinal vascular permeability.

Beovu delivers high molar concentration of anti-VEGF activity in a compact 27.6mg/0.23ml dosage form, enabling researchers to model retinal neovascularization, angiogenesis inhibition, and anti-VEGF pathways in both in vitro and in vivo settings.

?? This product is strictly intended for laboratory research use and is not approved for human or veterinary administration.

Product Specifications

Mechanism & Research Applications

Brolucizumab binds VEGF-A with high affinity, preventing interaction with VEGF receptors on endothelial cells, thereby suppressing angiogenesis and vascular leakage. It enables researchers to investigate:

• Pathogenesis and treatment of wet age-related macular degeneration (wet AMD)

• Experimental retinal angiogenesis models

• Comparative efficacy of anti-VEGF agents

• VEGF pathway inhibition and downstream signaling

• Ocular pharmacokinetics of antibody fragments

Observed Effects in Research Models

In preclinical studies, Brolucizumab has shown:

• Potent inhibition of neovascularization

• Reduction in retinal thickness and fluid accumulation

• Minimal systemic exposure due to small molecular size

• Transient inflammation in animal eye models (dose-dependent)

Appropriate research protocols and animal care guidelines should be followed.

Safety & Handling

• Use Restriction: Laboratory research use only.

• Personal Protective Equipment: Gloves, goggles, lab coat

• Storage: Refrigerate (2–8°C); avoid freezing

• Disposal: Dispose of biological waste per local biosafety guidelines

Research Use Disclaimer

This product is strictly intended for laboratory research use only. It is not for clinical, therapeutic, diagnostic, or veterinary use. Misuse may result in legal or health risks. Always follow institutional biosafety and handling protocols.