描述
Buspirone is a non-benzodiazepine anxiolytic that functions as a 5-HT1A receptor partial agonist, making it ideal for research into anxiety modulation, serotonin pathways, and central nervous system pharmacology. Unlike traditional anxiolytics, it does not exhibit sedative or muscle relaxant effects, offering a cleaner mechanism of action in research settings.
Buspirone Hydrochloride Product Specifications
Parameter | Details |
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Product Name | Buspirone Hydrochloride Tablets |
Generic Name | Buspirone Hydrochloride |
CAS Number | 36505-84-7 |
Molecular Formula | C21H31N5O2·HCl |
Molecular Weight | ~421.96 g/mol |
Formulation | Oral Tablets |
Strength | 5?mg per tablet |
Pack Size | 2 plates × 10 tablets (20 tablets per box) |
Approval Number | H20000199 (NMPA, China) |
Drug Code | 86900052000235 |
Manufacturer | Beijing Huasu Pharmaceutical Co., Ltd. |
Product Barcode | 6931837200209 |
Storage | Store in a cool, dry place below 25?°C |
Intended Use | For scientific/laboratory research only |
Buspirone Hydrochloride Mechanism of Action
Buspirone acts as a partial agonist at serotonin 5-HT1A receptors and exhibits affinity for dopamine D2 receptors, allowing researchers to explore its dual serotonergic-dopaminergic interaction. This profile is essential for investigating non-sedative anxiolytic agents, neuroplasticity, and psychotropic regulation in experimental models.
Buspirone Hydrochloride Research Applications
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Anxiety Research Models
Ideal for preclinical studies evaluating anxiolytic properties and 5-HT1A receptor activity. -
Neurochemical Modulation
Explores serotonergic and dopaminergic interactions in the central nervous system. -
Psychopharmacology Studies
Suitable for evaluating behavior, mood regulation, and synaptic signaling. -
Drug Interaction Research
Often used as a baseline compound in comparative studies on anxiolytics.
Safety & Handling
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Usage: Authorized lab personnel only.
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Handling: Use protective gloves, goggles, and lab-grade PPE.
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Storage: Store in original packaging in a controlled environment.
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Stability: Stable for up to 36 months under dry, dark conditions.
Research Use Disclaimer
This product is provided exclusively for research and analytical purposes. It is not intended for diagnostic, therapeutic, or clinical applications in humans or animals. Improper handling may result in safety hazards. Always follow institutional lab safety guidelines.
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