Busulfan Injection 60?mg Price comparison
$1.00
Busulfan Injection (brand: Yilai, BaiXiaoAn) is a cytotoxic alkylating agent used for preconditioning in hematopoietic stem cell and chronic myeloid leukemia (CML) research. Supplied as a 60?mg freeze-dried injection in 10?ml vials, 10 vials per box. Manufactured by China Resources Double-Crane Pharmaceutical Co., Ltd., approved under China NMPA H20183147.
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Busulfan Injection (BaiXiaoAn / Yilai) |
| Generic Name | Busulfan (1,4-Butanediol dimethanesulfonate) |
| Dosage Form | Lyophilized injection |
| Strength | 60?mg / 10?ml per vial |
| Pack Size | 10 vials per box |
| Approval Number | H20183147 (China NMPA) |
| Product Code | 86981661000076 |
| Manufacturer | China Resources Double?Crane Pharmaceutical Co., Ltd. |
| Barcode | 6921789020444 |
| Storage | Store at 2–8?°C, protect from moisture |
| Intended Use | Laboratory research only |
Mechanism of Action
Busulfan is an alkyl sulfonate that crosslinks DNA, leading to cell cycle arrest and apoptosis. It is typically used as part of preconditioning regimens in hematopoietic stem cell transplantation for CML models dcpc.com+8zh.wikipedia.org+8pmc.ncbi.nlm.nih.gov+8.
Research Applications & Pharmacology
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Preconditioning agent: Used with Cyclophosphamide for conditioning mice in stem cell transplant studies .
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CML research: Models for chronic myeloid leukemia and bone marrow ablation.
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Cell biology: Studies on DNA crosslink damage and repair.
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In vivo dosing: Typically 100?mg/kg in animal models.
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Pharmacokinetics: Short half-life (~2.5 hrs); hepatic metabolism; oral bioavailability ~80% .
Safety Profile & Side Effects
Common Research Observations
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Hematologic suppression: leukopenia, thrombocytopenia, anemia
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Pulmonary toxicity: potential fibrosis
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Hepatotoxicity: elevated liver enzymes
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Neurologic: seizures at high doses; anticonvulsant prophylaxis recommended
Handling & Storage Notes
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Use PPE, handle under sterile conditions
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Reconstitute and administer using aseptic technique
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Dispose of waste as hazardous
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Store vials refrigerated; protect from moisture and light
?? Research?Use Disclaimer
This product is intended for use only in laboratory research. Not approved for therapeutic, diagnostic, or veterinary uses. Misuse may pose serious risks or invalidate experimental results.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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