描述
Salmon Calcitonin is a 32?amino-acid peptide hormone with high potency in reducing osteoclastic bone resorption and stimulating osteoblastic bone formation. It acts as a dual agonist at calcitonin and amylin receptors, supporting applications in bone metabolism, cardiovascular, and metabolic research.
Our product is manufactured in GMP-compliant peptide synthesis facilities, tested to ?99.95% purity by HPLC, and shipped with a full Certificate of Analysis (COA) and lot traceability. Supplied as white to off?white lyophilized powder.
?? Intended for laboratory research use only and not approved for therapeutic or diagnostic use.
Calcitonin (salmon) Product Specifications
Parameter | Specification |
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Product Name | Calcitonin (salmon) |
Synonyms | Salmon calcitonin, sCT, DACRA prototype |
CAS Number | 47931?85?1 |
Purity (HPLC) | ?99.95% |
Sequence | Cys?Ser?Asn?Leu?Ser?Thr?Cys?Val?Leu?Gly?Lys?Leu?Ser?Gln?Glu?Leu?His?Lys?Leu?Gln?Thr?Tyr?Pro?Arg?Thr?Asn?Thr?Gly?Ser?Gly?Thr?Pro?NH? |
Molecular Weight | ~3,431.7 Da |
Appearance | White to off?white lyophilized powder |
Mechanism | Dual amylin and calcitonin receptor agonist |
Solubility | Soluble in acidic aqueous buffer (~1?mg/mL) |
Source | Synthetic peptide, non-animal derived |
Manufacture | GMP-compliant peptide synthesis facility |
Storage | ?20?°C or colder; protect from light and moisture |
Packaging | 1?mg, 5?mg, 10?mg vials or bulk |
Intended Use | Research use only; not for human or veterinary use |
Calcitonin (salmon) Mechanism of Action & Research Applications
Salmon Calcitonin binds calcitonin receptors to inhibit bone resorption and, as a dual agonist at amylin receptors, enhances metabolic effects including appetite suppression and energy balance. It is used for:
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Bone metabolism and osteoporosis modeling
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Studies on osteoclast/osteoblast signaling
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Dual receptor pharmacology in metabolic research
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Exploration of anti-resorptive and anabolic bone pathways
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Models of osteoarthritis, liver fat metabolism, and nociception
The product’s GMP-grade traceability and ultra-high purity support reproducible results in advanced preclinical studies.
Calcitonin (salmon) Side Effects (For Laboratory Reference Only)
In experimental or in vivo models, high doses of salmon calcitonin may cause:
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Mild gastrointestinal effects
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Transient hypotension via vasodilatory response
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Hormonal modulation affecting calcium metabolism
Use appropriate dose control and ethical protocols for animal studies.
Disclaimer
This product is intended solely for laboratory research use. It is not approved for clinical, therapeutic, or diagnostic use in humans or animals. Handle per institutional safety guidelines.
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