描述
Capecitabine Tablets Product Specifications
Attribute | Details |
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Product Name | Capecitabine Tablets (Shanghai Synyi) |
Strength | 0.5?g per tablet |
Quantity | 12 tablets per box |
Formulation | Oral tablet |
Approval No. | China NMPA H20233900 |
Product Code | 86981288000046 |
Barcode | 6920257000162 |
Manufacturer | Shanghai Shenyang Yiying Pharmaceutical Co., Ltd. |
Intended Use | Laboratory research use only — Not for human or veterinary use |
Mechanism of Action
Capecitabine is a tumor-selective prodrug of 5?fluorouracil (5-FU). Once ingested, it is converted to 5-FU in tumors by thymidine phosphorylase, disrupting DNA synthesis via thymidylate synthase inhibition and blocking RNA function .
Research & Reference Data
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High oral bioavailability (~100%), with C??? at ~1.5–2?h; primarily excreted renally (~95%) .
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Widely used as a standalone or combination therapy in colorectal, breast, gastric, and pancreatic cancer en.wikipedia.org+3pubmed.ncbi.nlm.nih.gov+3mayoclinic.org+3.
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Common toxicities include diarrhea, hand-foot syndrome, mucositis, myelosuppression, elevated bilirubin; watch for DPD deficiency?linked severe toxicity
Research Applications
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In vitro/in vivo tumor models (e.g., colorectal, breast cancer)
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Drug metabolism and pharmacokinetic studies
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Toxicity profiling and DPD-deficiency modeling
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Combination therapy exploration with chemotherapeutics or targeted agents
?? Research?Use Disclaimer
This product is provided strictly for laboratory research and development use only. Not intended for human, veterinary, clinical, diagnostic, or therapeutic applications.
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