Desvenlafaxine Succinate SR Tablets 50mg

Desvenlafaxine Succinate SR Tablets 50mg

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Desvenlafaxine Succinate Sustained-release Tablets (50mg) are extended-release formulations of a serotonin-norepinephrine reuptake inhibitor (SNRI), useful in experimental studies related to depression, mood regulation, and neurochemical imbalance. Manufactured by CSPC Ouyi Pharmaceutical Co., Ltd. and approved under Chinese NMPA H20233840. Intended strictly for scientific research use.?? For laboratory research only.?Please consult staff for other specifications and uses?

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描述

Desvenlafaxine is the active metabolite of venlafaxine and functions as an SNRI. It is often utilized in preclinical CNS studies examining neurotransmitter uptake inhibition, mood disorders, and neuroplasticity. This sustained-release formulation ensures prolonged plasma concentration for extended pharmacodynamic observation.


Desvenlafaxine Succinate Product Specifications

Parameter Details
Product Name Desvenlafaxine Succinate Sustained-release Tablets
Synonyms Desvenlafaxine ER, DVS, O-desmethylvenlafaxine
CAS Number 93413-62-8
Molecular Formula C16H25NO2
Molecular Weight 263.38 g/mol
Strength 50mg per tablet
Formulation Sustained-release tablet
Pack Size 14 tablets per box
Dosage Form Oral tablet
Approval Number H20233840 (NMPA, China)
Drug Code 86902770004779
Manufacturer CSPC Ouyi Pharmaceutical Co., Ltd.
Storage Conditions Store below 25°C, away from moisture
Intended Use Laboratory research only

Desvenlafaxine Succinate Mechanism of Action

Desvenlafaxine acts by selectively inhibiting the reuptake of serotonin and norepinephrine in the CNS. It increases the synaptic concentration of these neurotransmitters, helping stabilize mood in experimental models. Its sustained-release formulation ensures consistent drug levels in long-duration studies.


Research Applications

  • Mood Disorder Models
    Supports the evaluation of SNRI efficacy in depressive and anxiety-like behaviors in rodents or in vitro systems.

  • Neurotransmitter Studies
    Useful in serotonin-norepinephrine transport and receptor pathway mapping.

  • Chronic Stress Research
    Employed in chronic mild stress and neuroendocrine axis studies to simulate human depressive pathology.

  • Drug-Drug Interaction Studies
    Used in CYP metabolism and transporter interaction profiling.


Safety & Handling

  • Handling: Use standard protective equipment in research environments.

  • Storage: Keep sealed and dry at room temperature (?25°C).

  • Shelf Life: Stable up to 24–36 months when properly stored.

  • Disclaimer: Not suitable for human or veterinary use.


Research Use Only Disclaimer

This product is designated solely for laboratory research. It is not intended for therapeutic, diagnostic, clinical, or human consumption. Handle according to institutional biosafety guidelines.

其他信息

重量 1.2 公斤
尺寸 62 × 23 × 62 厘米

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Q1: What is the difference between venlafaxine and desvenlafaxine?

A1: Desvenlafaxine is the active metabolite of venlafaxine and has more predictable pharmacokinetics.

Q2: What makes this sustained-release (SR)?

A2: It’s designed for extended release to maintain therapeutic levels over a longer period for prolonged CNS effect observation.

Q3: Can this be used in behavioral animal models?

A3: Yes, it’s frequently used in depressive and anxiety disorder models in rodents for CNS research.

Q4: Can I request COA/SDS?

A4: Yes, Certificates of Analysis and Safety Data Sheets are available upon request.

Q5: Do you support large wholesale orders?

A5: Absolutely. We support both small lab quantities and bulk institutional procurement.


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