Description

Entecavir is a potent guanosine nucleoside analogue that inhibits hepatitis B virus replication. Designed as a dispersible tablet, it dissolves quickly in water, ensuring rapid absorption. It’s ideal for pharmacological research, viral load suppression studies, and comparative analysis in HBV models. Clinically utilized to lower HBV DNA levels and prevent disease progression in chronic HBV patients with active viral replication or elevated ALT/AST.

Entecavir Dispersible Product Specifications

Entecavir Dispersible Mechanism of Action

Entecavir functions as a nucleoside reverse transcriptase inhibitor (NRTI), targeting and inhibiting hepatitis B virus polymerase. It effectively blocks viral DNA synthesis at multiple stages, resulting in potent suppression of HBV replication—making it a cornerstone in HBV treatment and research .

Research & Clinical Applications

• Chronic hepatitis B viral suppression

• Comparative antiviral efficacy studies

• Resistance development and mutation analysis

• Pharmacokinetic and absorption profiling (dispersible form)

• Elevated ALT/AST reduction studies

• Lamivudine-resistant HBV models

Safety & Handling

• Adverse effects (in trials): headache, fatigue, nausea, dizziness, potential renal adjustments

• Storage: Keep sealed in original packaging at ??25?°C

• Handling: Use proper PPE—gloves, lab coat, safety eyewear. Avoid ingestion and contact.

Core  Keywords

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Research Use Disclaimer

Strictly for laboratory research and clinical investigation. Not approved for therapeutic, diagnostic, veterinary, or personal use. Improper use may lead to health or legal hazards—must follow institutional protocols.