描述
Ibandronate Sodium is a potent nitrogen-containing bisphosphonate studied extensively for its inhibitory effect on osteoclast-mediated bone resorption. It is frequently used in preclinical studies on osteoporosis, hypercalcemia, metastatic bone disease, and other conditions involving bone metabolism dysregulation.
This injectable formulation offers 2mg of ibandronate per 2ml ampoule, ensuring precision and purity for controlled experimental conditions in in vivo and in vitro research.
?? This product is not approved for human or veterinary use. Laboratory use only.
Product Specifications
Parameter | Details |
---|---|
Product Name | Ibandronate Sodium Injection (Aimeikun / ???) |
Active Ingredient | Ibandronate Sodium |
CAS Number | 138928-22-8 |
Molecular Formula | C?H??NO?P?Na |
Molecular Weight | 319.14 g/mol (base) |
Strength | 2mg/2ml |
Dosage Form | Injection |
Quantity per Box | 1 vial per box |
Approval Number | ????H20123094 |
Product Code | 86902181000445 |
Manufacturer | Chengdu Yuandong Biopharmaceutical Co., Ltd. (??????????????) |
Barcode | 6950425900116 |
Storage Conditions | Store below 25?°C in a dry place; protect from light |
Intended Use | For laboratory research only |
Mechanism of Action
Ibandronate works by binding to hydroxyapatite in bone tissue and inhibiting osteoclast-mediated bone resorption. This action decreases bone turnover and maintains bone density, making it suitable for models involving:
-
Osteoporosis
-
Bone metastases
-
Tumor-induced hypercalcemia
-
Skeletal-related events in oncology research
Research Applications
-
Bone density and turnover studies
-
Osteoclast activity models
-
Metastatic bone lesion research
-
Calcium metabolism studies
-
Oncology and skeletal support research
Side Effects (Observed in Lab Studies)
-
Injection site irritation
-
Hypocalcemia (dose-dependent)
-
Flu-like symptoms in rodent models
-
Transient increase in bone resorption markers
-
Renal stress at high systemic dosages
Safety & Handling
-
Use: Research-only chemical; not for medical use
-
PPE: Lab gloves, mask, and protective eyewear recommended
-
Handling: Avoid skin or eye contact; handle in sterile conditions
-
Storage: Store in original sealed vial below 25?°C
-
Disposal: Dispose according to biosafety and chemical waste guidelines
Core Keywords
Ibandronate Sodium injection, CAS 138928-22-8, bisphosphonate research, osteoporosis lab model, bone resorption inhibitor, ibandronate Aimeikun, lab-use only injection, bone metabolism research, injectable bisphosphonate, wholesale ibandronate sodium
Research Use Disclaimer
This product is intended strictly for laboratory research use only. It is not approved for use in humans or animals, for diagnostic procedures, or for therapeutic applications. Improper use may lead to health hazards. Handle under guidance of trained professionals and according to institutional biosafety regulations.
评价
目前还没有评价