Mechlorethamine Hydrochloride Injection (HaiPu®) – 1?mL:5?mg Vial Price Comparison
$1.00
Mechlorethamine hydrochloride (HaiPu®) is a potent DNA-alkylating agent from the nitrogen mustard class, supplied as a 1?mL vial containing 5?mg. Manufactured by Shanghai Xudong Haipu Pharmaceutical Co., Ltd., with NMPA approval H31020897 and product code 86900808000625. Strictly for laboratory research use.?Please consult the staff for other purposes?
描述
Mechlorethamine-Hydrochloride-Injection Specifications
| Attribute | Details |
|---|---|
| Product Name | Mechlorethamine Hydrochloride Injection (HaiPu®) |
| Concentration | 5?mg mechlorethamine hydrochloride per 1?mL vial |
| Dosage Form | Injectable solution (vial) |
| Approval No. | China NMPA H31020897 |
| Product Code | 86900808000625 |
| Manufacturer | Shanghai Xudong Haipu Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research use only—Not for human or veterinary use |
Mechlorethamine Hydrochloride Injection Background & Mechanism
Mechlorethamine is a nitrogen mustard alkylating agent that induces DNA cross-linking to inhibit DNA synthesis and trigger apoptosis. Its powerful cytotoxic nature stems from forming bifunctional adducts with DNA, particularly guanine residues . Although once used clinically, its high toxicity led to a decline in therapeutic use, making it largely a research chemical today .
Mechlorethamine Hydrochloride Injection Safety & Storage
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Carcinogenicity warning: Classified as a probable human carcinogen ntp.niehs.nih.gov.
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Storage: Protect from light; store in tightly sealed vials; may degrade quickly in solution.
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Handling: Use lab-grade PPE (gloves, gown, eye protection). Administer only in ventilated biosafety cabinets due to inhalation and contact hazard.
Mechlorethamine-Hydrochloride-Injection Research Applications
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DNA crosslinking assays
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Cytotoxicity screening and DNA damage studies
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Modeling alkylation-based genotoxic stress
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Mechanisms of repair pathway research (e.g., NER, HR)
?? Disclaimer
This product is provided strictly for laboratory research and development use only. Not intended for human, veterinary, clinical, diagnostic, or therapeutic applications.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 18 × 16 厘米 |
Mechlorethamine Hydrochloride Injection (HaiPu®) – 1?mL:5?mg Vial Price Comparison 有 1 个评价
A1: No—strictly for laboratory research only, not intended for therapeutic, diagnostic, or veterinary use.
A2: It alkylates DNA at guanine N7 positions, causing cross-links that prevent replication and lead to apoptosis
A3: Highly toxic and carcinogenic. Requires strict handling protocols, disposal procedures, and protective equipment.
A4: Keep in original vial, protected from light, and refrigerated when not in use. Reconstitute under biosafety conditions and use immediately due to instability.
A5: Yes—available upon request for qualified research labs.
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