描述
Metoclopramide Hydrochloride Product Specifications
Specification | Description |
---|---|
Product Name | Metoclopramide Hydrochloride Injection (Furen) |
Generic Name | Metoclopramide HCl |
CAS Number | 364?62?5 medlineplus.gov+8en.wikipedia.org+8punchout.medline.com+8 |
Formulation | Sterile aqueous injection, 10?mg/mL |
Strength | 10?mg metoclopramide per 1?mL vial |
Pack Size | 10 vials × 1?mL per box |
Approval Number | H41024089 (NMPA, China) |
Drug Code | 86903139001330 |
Manufacturer | Kaifeng Pharmaceutical Group Co., Ltd |
Storage Conditions | Store below 30?°C in a cool, dry, well-ventilated place; protect from light |
Intended Use | For laboratory research only |
Metoclopramide Hydrochloride Mechanism of Action
Metoclopramide is a dopamine D? receptor antagonist, serotonergic (5-HT? antagonist, 5-HT? agonist), and stimulates gastrointestinal motility, reducing nausea and accelerating gastric emptying .
Research Applications & Pharmacology
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GI motility models: key agent in gastroparesis and reflux physiology research
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Antiemetic pathways: widely used in PONV and CINV research, as well as migraine-related emesis
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Pharmacodynamics studies: data on dopamine/serotonin receptor interaction and prazocin regulation
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Drug interaction assays: inhibits CYP2D6; used to study CNS and hepatic metabolism pathways
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PK/PD profiling: intravenous dosing models suitable for small-animal research
Safety Profile & Handling
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Preclinical safety: Generally well-tolerated in lab conditions; watch for sedation and GI motility changes
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Known side effects: extrapyramidal effects, tardive dyskinesia risk with prolonged exposure
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Laboratory precautions: use PPE—gloves, safety goggles,?lab coat; avoid inhalation/contact
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Storage: cool, dry, light-protected environment
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Disposal: dispose via biohazard/pharmaceutical protocols
Core Keywords
metoclopramide injection, metoclopramide HCl, antiemetic research chemical, gastric motility agent, CAS 364-62-5, wholesale metoclopramide, VIP lab reagent
Research?Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Improper handling or use may pose health risks—follow institutional safety guidelines.
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