描述
Olanzapine Injection Product Specifications
Specification | Details |
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Product Name | Olanzapine Injection (Xingke) |
Generic Name | Olanzapine |
CAS Number | 132539?06?1 (PubChem CID: 4585) |
Molecular Formula | C??H??N?S () |
Molecular Weight | 312.44?g/mol () |
Formulation | Sterile freeze-dried powder for intramuscular injection |
Strength | 10?mg per vial |
Pack Size | 1 vial per box (or as specified) |
Approval Number | H20254739 (NMPA, China) |
Manufacturer | Qilu Pharmaceutical Co., Ltd. |
Storage Conditions | Store at 2–8?°C; protect from light and moisture |
Intended Use | For laboratory research only |
Mechanism of Action
Olanzapine, a second-generation (atypical) antipsychotic, antagonizes dopamine D? and serotonin 5-HT?A receptors, modulating multiple neurotransmitter systems. This supports research in psychosis, mood disorders, and neurochemical pathways.
Research Applications & Pharmacology
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Neuropsychiatric models: Ideal for schizophrenia and bipolar disorder preclinical assays, including acute agitation and cognitive deficits.
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Receptor-binding assays: Studies on D?, 5-HT?A, histamine H?, and muscarinic receptors.
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Pharmacokinetic profiling: Assess absorption, distribution, metabolism, and elimination—comparable to intramuscular standards.
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Disorder modeling: Used in metabolic syndrome, weight gain, and extrapyramidal side effect assays.
Safety Profile & Handling
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Preclinical effects: May cause somnolence, hypotension, weight gain, and metabolic changes. Enhanced mortality risk in elderly dementia models.
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Handling: Use gloves and masks. Reconstitute aseptically. Inspect for particulates.
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Storage: Keep refrigerated at 2–8?°C, shielded from light.
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Disposal: Label as chemical/pharmaceutical waste per lab regulations.
Core Keywords
olanzapine injection, lab-grade olanzapine, CAS 132539?06?1, antipsychotic research reagent, schizophrenia preclinical model, bipolar mania assay, receptor-binding olanzapine, Qilu Pharma olanzapine
Research?Use Disclaimer
This product is intended only for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may pose health risks. Always comply with institutional safety guidelines.
simoki –
The package was well packed, I received it, thank you