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Pradefovir Mesylate Tablets 45?mg (Xinshumu)
$1.00
Xinshumu Pradefovir Mesylate Tablets deliver 45?mg of pradefovir per tablet in a 30-tablet bottle. Manufactured by Xi’an Gelan Xintong Pharmaceutical Co., Ltd., with NMPA approval H20240036. Designed for preclinical and laboratory research on hepatitis B viral suppression and liver-targeted antiviral therapy.
?? For laboratory and research use only.?Please consult staff for other specifications and uses?
Description
Pradefovir is an innovative liver-targeted nucleotide prodrug of adefovir that inhibits HBV reverse transcriptase, demonstrating potent and specific antiviral effects. It remains stable in plasma and GI, activated in the liver via CYP3A4, leading to lower systemic exposure and improved safety. Clinical studies show efficacy equivalent to tenofovir disoproxil with fewer renal/bone side effects.
Pradefovir Mesylate Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Pradefovir Mesylate Tablets (Xinshumu) |
| Generic Name | Pradefovir Mesylate |
| CAS Number | 625095?60?5 |
| Molecular Formula | C??H??ClN?O?P |
| Molecular Weight | ~423.8?g/mol |
| Strength | 45?mg per tablet (based on C??H??ClN?O?P) |
| Pack Size | 30 tablets per bottle |
| Dosage Form | Oral film-coated tablet |
| Approval No. | H20240036 (NMPA) |
| Drug Code | 86909589000053 |
| Manufacturer | Xi’an Gelan Xintong Pharmaceutical Co., Ltd. |
| Barcode | 6976282808051 |
| Storage Conditions | Store <25?°C, sealed, protected from light and moisture |
| Intended Use | Laboratory or preclinical HBV antiviral research |
Pradefovir Mesylate Tablets Mechanism of Action
Pradefovir is a liver-directed prodrug that converts via CYP3A4 to adefovir, which inhibits HBV DNA polymerase, effectively blocking viral replication. Its hepatoselective design reduces systemic exposure and enhances safety.
Pradefovir Mesylate Tablets Research Applications
Chronic HBV replication suppression
Pharmacokinetic and pharmacodynamic profiling in liver-targeted therapy
Resistance and safety comparison with first-line antiviral agents
Preclinical studies on long-term antiviral efficacy and toxicity
Safety & Handling
Handling: Use PPE—gloves, lab coat, goggles—avoid ingestion and contact.
Storage: Keep sealed below 25?°C in a dry, light-protected environment.
Precautions: For laboratory use only; not for human or veterinary administration.
Core Keywords
pradefovir tablets, pradefovir mesylate 45mg, CAS 625095?60?5, H20240036, antiviral prodrug, liver targeted HBV drug, Xinshumu pradefovir, wholesale pradefovir
Research Use Disclaimer
For laboratory and preclinical research use only. Not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may pose health or regulatory risks. Use under authorized institutional protocols.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 26 × 21 × 26 cm |
1 review for Pradefovir Mesylate Tablets 45?mg (Xinshumu)
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