Pregabalin Extended-release Tablets 165?mg × 8 Tablets Rui Bei Hu
$1.00
Pregabalin Extended-release Tablets (brand name: Rui Bei Hu) contain 165?mg of pregabalin per tablet. Supplied in 8-tablet packaging, this formulation is manufactured by Jiangsu Hengrui Pharmaceutical Co., Ltd.. Designed for sustained plasma levels in preclinical neurological studies, it is suitable for laboratory research in neuropathic pain, epilepsy, and generalized anxiety disorder models.?? For laboratory research use only.?Please consult staff for other specifications and uses?
描述
Pregabalin is a GABA-analog compound widely used in CNS research. The extended-release (ER) format supports longer half-life and more stable plasma levels in test models, making it valuable for chronic pain, seizure, and anxiety-related pharmacology.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Pregabalin Extended-release Tablets |
| Brand Name | ??? (Rui Bei Hu) |
| Active Ingredient | Pregabalin |
| CAS Number | 148553-50-8 |
| Molecular Formula | C8H17NO2 |
| Molecular Weight | 159.23 g/mol |
| Strength | 165?mg per tablet |
| Formulation | Sustained-release (ER) oral tablets |
| Pack Size | 8 tablets per box |
| Approval Number | H20210042 (China NMPA) |
| Drug Code | 86901445003321 |
| Manufacturer | Jiangsu Hengrui Pharmaceutical Co., Ltd. |
| Storage Conditions | Store in cool, dry place (15–25°C); avoid light and moisture |
| Research Use | For laboratory research only |
Mechanism of Action
Pregabalin binds to the ?2? subunit of voltage-gated calcium channels in the CNS, reducing calcium influx and subsequently decreasing the release of excitatory neurotransmitters like glutamate and substance P. This mechanism contributes to its efficacy in models of neuropathic pain, epilepsy, and anxiety.
Research Applications
-
Neuropathic Pain Models
Effective in sciatic nerve ligation, diabetic neuropathy, and spinal nerve transection models. -
Epilepsy and Seizure Research
Reduces seizure frequency in animal models with chemically or electrically induced epilepsy. -
Anxiety and Depression Research
Demonstrates anxiolytic properties in behavioral tests (e.g., elevated plus maze, light/dark box). -
Chronic Pain/Inflammation
Useful for long-term dosing due to extended-release formulation.
Safety & Handling
-
Handling Instructions: Use gloves and protective gear when preparing or handling tablets.
-
Storage: Keep sealed at room temperature in dry conditions.
-
Shelf Life: Generally stable for up to 36 months.
-
Toxicological Profile: Overexposure may result in dizziness, sedation, or behavioral changes in lab animals.
Research Use Disclaimer
This product is strictly intended for scientific laboratory research. It is not approved for therapeutic, diagnostic, or veterinary use. Misuse may result in health risks. Please follow institutional guidelines and local regulations when handling.
其他信息
| 重量 | 1.2 公斤 |
|---|---|
| 尺寸 | 52 × 43 × 52 厘米 |
A1: ER (Extended-release) tablets release pregabalin slowly over time, offering longer duration in research protocols without frequent re-dosing.
A2: Yes, this version is intended exclusively for laboratory use, not for clinical or diagnostic purposes.
A3: Yes, all technical documents (COA, SDS, TDS) are available upon request.
A4: Rodent models for diabetic neuropathy, spinal nerve ligation, chronic constriction injury, and epilepsy.
A5: Absolutely. We support OEM labeling and wholesale supply. Please contact us for pricing.
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