Rilertinib Mesylate Tablets (Sanrisso®) – 100?mg × 20 Tablets per Bottle

Rilertinib Mesylate Tablets (Sanrisso®) – 100?mg × 20 Tablets per Bottle

(1 条用户评价)

$1.00

Rilertinib mesylate (Sanrisso®), developed by Nanjing Sanhome Pharmaceutical Co., Ltd., is a third-generation EGFR-TKI approved by China’s NMPA (Approval No. H20240020; Drug Code: 86901583000930). Each bottle contains 20 tablets of 100?mg each. Strictly for laboratory research use only—not for clinical or human use.

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描述

Rilertinib Mesylate Product Specifications

Attribute Details
Product Name Rilertinib Mesylate Tablets (Sanrisso®)
Dosage 100?mg per tablet × 20 tablets per bottle
Formulation Oral film-coated tablet
Approval No. China NMPA H20240020
Drug Code 86901583000930
Manufacturer Nanjing Sanhome Pharmaceutical Co., Ltd.
Intended Use Laboratory research only—Not for human or veterinary use

? Overview & Mechanism

Rilertinib mesylate (Sanrisso®) is a third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that targets activating mutations and the T790M resistance mutation in non-small cell lung cancer (NSCLC). It exhibits potent anti-tumor activity against EGFR-mutant NSCLC cell lines and tumor models.


? Research & Clinical Context

  • China NMPA Approval (Feb 2025): Approved for patients with EGFR T790M mutation-positive advanced or metastatic NSCLC after progression on prior EGFR-TKI therapy.

  • Phase III Trials: Demonstrated superior progression-free survival (PFS) compared to gefitinib in EGFR-mutant NSCLC patients.


? Research Applications

Ideal for:

  • EGFR pathway and T790M-resistance mechanisms

  • In vitro and in vivo NSCLC models

  • Drug resistance and combination therapy studies

  • Pharmacokinetic and pharmacodynamic profiling


? Handling & Storage

  • Storage: Store at 20–25?°C, sealed and protected from light and moisture.

  • Handling: Use appropriate laboratory personal protective equipment (PPE); avoid ingestion or inhalation.


? References

  • NMPA approval announcement (Feb 19, 2025)

  • Phase III trial results comparing rilertinib vs gefitinib

  • Drug mechanism and development synopsis

其他信息

重量 1.1 公斤
尺寸 26 × 25 × 26 厘米

Rilertinib Mesylate Tablets (Sanrisso®) – 100?mg × 20 Tablets per Bottle 有 1 个评价

  1. tinknocke

    The logistics was very fast, I received it in 8 days

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