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Rimtoregtide – High Purity 98% – GMP Manufacturer
$2.00
Rimtoregtide is a GMP-grade polypeptide (purity ? 98%) derived from Reg3?, effective in reducing markers of acute pancreatitis (amylase, lipase) in preclinical models. Ideal for gastrointestinal inflammation and pancreatitis research. For laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Rimtoregtide (CAS No. 2251722-35-5) is a synthetic polypeptide derived from the Reg3? protein. It has demonstrated significant protective effects in preclinical models of acute pancreatitis by attenuating elevated levels of pancreatic enzymes—amylase and lipase—and improving survival and tissue integrity. This compound exhibits immunomodulatory and anti-inflammatory properties, offering valuable utility in research on pancreatic injury, acute inflammation, and related disorders. Manufactured under GMP standards with high purity (? 98%), Rimtoregtide delivers reliable reproducibility for experimental applications. Intended strictly for laboratory research use only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Rimtoregtide |
| Synonyms | HTD4010; Reg3?-derived peptide |
| CAS No. | 2251722-35-5 |
| Purity | ? 98% (GMP-grade) |
| Molecular Formula | C??H???N??O?? |
| Molecular Weight | Approximately 1500.6 g/mol |
| Mechanism | Polypeptide with anti-pancreatitis and inflammatory modulation activity |
| Appearance | White to off-white powder |
| Solubility | Soluble in aqueous buffers; mild heating or sonication may aid dissolution |
| Storage Conditions | Store at –20 °C; protect from light and moisture |
| Manufacturing Standard | GMP-compliant |
| Applications | Acute pancreatitis models, pancreatic injury research, inflammatory response studies |
| Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
Mechanism of Action:
Rimtoregtide is derived from the Reg3? protein and exhibits protective, immunomodulatory effects in models of acute pancreatitis. It mitigates elevated enzyme markers (amylase and lipase), improves survival, and reduces multi-organ injury in affected subjects.
Research Applications:
Acute Pancreatitis Models: Highly relevant for experimental studies evaluating pancreatic injury and inflammation.
Inflammatory Response Studies: Suitable for investigating immunomodulation and tissue protection.
Pancreatic Enzyme Regulation: Useful in assays assessing enzyme level modulation and related signaling pathways.
Preclinical Drug Evaluation: Facilitates exploration of therapeutic candidates for pancreatitis or related acute inflammatory disorders.
Side Effects (Research Context Only)
Rimtoregtide is strictly intended for in vitro and preclinical model use. In animal studies, it showed protective effects with improved survival and reduced organ damage; specific safety profiles for humans are not available. Standard laboratory safety protocols should be observed.
Disclaimer
Rimtoregtide is strictly for laboratory research use only. It is not approved for any clinical, therapeutic, or diagnostic applications. Please adhere to your institution’s safety and handling guidelines.
Additional information
| Weight | 0.65 kg |
|---|---|
| Dimensions | 58 × 26 × 58 cm |
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