Tislelizumab Injection 100?mg Factory wholesale price
$1.00
Tislelizumab Injection (brand: Bangqi®), developed by Beigene/Boehringer Ingelheim, is a humanized monoclonal antibody targeting PD?1, used in preclinical immuno-oncology research. Supplied as 100?mg per 10?mL vial. Approved under China NMPA S20190045 (product code 86982097000012; barcode 6972467191888).
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Tislelizumab Injection (Bangqi®) |
| Generic Name | Tislelizumab |
| Brand | Bangqi® / Bangqi-Akynzeo® |
| CAS Number | 1858168?59?8 |
| Molecular Weight | ~147?kDa |
| Dosage Form | Sterile antibody solution for IV use |
| Strength | 100?mg per 10?mL vial |
| Pack Size | 1 vial per box |
| Approval Number | S20190045 (China NMPA) |
| Product Code | 86982097000012 |
| Manufacturer | Beigene (Guangzhou) / Boehringer Ingelheim China |
| Barcode | 6972467191888 |
| Storage | 2–8?°C, protect from light; discard after opening |
| Intended Use | Laboratory research only |
Mechanism of Action
Tislelizumab is an Fc-engineered humanized IgG4 monoclonal antibody that binds PD?1, blocking its interaction with PD?L1/PD?L2, thereby restoring T-cell–mediated immune responses against tumors. en.wikipedia.orgonclive.com+2accessdata.fda.gov+2aetna.com+2
? Research Applications & Pharmacology
-
Immuno-oncology studies: Models of esophageal, gastric, hepatic, and urothelial cancers
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Mechanistic research: PD?1/PD?L1 blockade, tumor microenvironment profiling, synergy with chemotherapy
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Pharmacokinetics: IV administration; t½ ~11–17 days; clearance ~0.15 L/day; exposures proportional at 200 mg Q3 weeks
Safety Profile & Precautions
Preclinical and clinical observations:
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Immune-mediated AEs: pneumonitis, colitis, hepatitis, endocrinopathies, nephritis, dermatologic reactions
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Infusion reactions: mild-to-severe (manage by slowing infusion)
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Hematologic changes: anemia, lymphopenia, neutropenia; metabolic (e.g., glucose, sodium changes)
Lab handling guidance:
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Use within biosafety environment; monitor renal/hepatic markers
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Screen for infection/endocrine endpoints in models
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Do not use in pregnant or immature animal models due to immune risk
?? Research?Use Disclaimer
This product is strictly for laboratory and preclinical research. It is not approved for any clinical, therapeutic, diagnostic, or veterinary purpose. Misuse may result in health risk or regulatory noncompliance.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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