Clodronate Disodium Capsules (Baiyunshan/Dewei) – 0.4?g × 10 Capsules Price comparison Subtotal: $2.00
Tropisetron Hydrochloride 25?mg
$1.00
Tropisetron Hydrochloride Injection (brand: Qiqiong®) is a highly selective 5?HT? receptor antagonist produced by Shandong Qidu Pharmaceutical Co., Ltd. (NMPA No.?H20163117; Code?86904145002007). Each ampoule delivers 5?mg in 5?mL (25?mg total, 5 amps/box, barcode?…). Commonly used to prevent chemotherapy- or surgery-induced nausea and vomiting in experimental models. Strictly for laboratory research use
描述
Tropisetron Hydrochloride Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Tropisetron Hydrochloride Injection (Qiqiong®) |
| Active Ingredient | Tropisetron Hydrochloride |
| Strength | 5?mg in 5?mL per ampoule |
| Quantity | 5 ampoules per box |
| Dosage Form | Aqueous injection solution |
| Approval No. (NMPA) | H20163117 |
| Product Code | 86904145002007 |
| Packaging | Ampoule ×?5 |
| Manufacturer | Shandong Qidu Pharmaceutical Co., Ltd. |
| Mechanism Class | 5?HT? receptor antagonist |
| Intended Use | Laboratory research only — Not for clinical or veterinary use |
Tropisetron Hydrochloride Mechanism of Action
Tropisetron selectively and competitively inhibits serotonin at 5?HT? receptors located peripherally (vagal nerve terminals in GI tract) and centrally (chemoreceptor trigger zone), thereby preventing the emetic reflex.
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Research & Pharmacology Context
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Used experimentally to model chemotherapy- or surgery-induced nausea and vomiting in animals. Typical first-day dose: 5?mg IV, followed by oral dosing for 5 days.
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Exhibits high plasma volume of distribution (400–600?L), protein binding (~60–71%), and variable half-life (7–30?hrs dependent on CYP2D6 metabolism).
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Also shows anti-inflammatory and neuroprotective effects via ?7-nicotinic acetylcholine receptor agonism in preclinical studies.
Research Applications
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Chemotherapy-induced emesis models (e.g., cisplatin-induced)
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Postoperative nausea protocols in animal studies
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Mechanism-of-action studies involving serotonin signaling
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Neuroprotection research, via ?7 nAChR pathways and inflammation modulation
?? Research?Use Only Disclaimer
This product is provided strictly for laboratory research and development use only. Not intended for clinical, veterinary, diagnostic, or therapeutic applications.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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