Tyrosylleucine – High Purity 99.43% – GMP Supplier

描述

Tyrosylleucine, with CAS number 17355-10-1, is a high-purity dipeptide composed of tyrosine and leucine, two essential amino acids known for their roles in protein synthesis and enzyme function. This peptide, with a purity of 99.43% (HPLC), is produced under GMP conditions, ensuring consistent quality and reliability for research applications.

As a component of various biologically active peptides, Tyrosylleucine is valuable for studying peptide interactions, protein folding, and the effects of specific amino acid pairings in biochemical processes. Additionally, this dipeptide serves as an important building block in synthetic peptide chemistry, enabling the development of more complex therapeutic peptides.

This product is available in lyophilized powder form for easy reconstitution in aqueous solutions or buffers, with packaging suitable for both small-scale research and larger, bulk orders for ongoing studies.

Product Specifications

Mechanism of Action & Research Applications

Mechanism of Action
Tyrosylleucine functions as a dipeptide with a unique combination of amino acids, contributing to protein synthesis and cell signaling pathways. Its structure allows it to participate in peptide bond formation, which can influence the stability and functionality of peptides in both synthetic and biological contexts. The combination of tyrosine and leucine is particularly useful for studying hydrophobic interactions and the stability of protein folding processes.

Research Applications

• Peptide Synthesis: Tyrosylleucine is used as a building block in the synthesis of custom peptides for research purposes, including the creation of peptides with specific biochemical properties.

• Enzyme Studies: It plays a role in studying the influence of amino acid pairs on enzyme activity and substrate specificity.

• Protein Folding: Researchers use Tyrosylleucine to study how the incorporation of specific amino acids affects protein conformation and stability.

• Drug Discovery: This dipeptide can be used in drug development studies, particularly for exploring peptide-based therapeutics.

• Cancer Research: As part of larger peptides, Tyrosylleucine has applications in developing targeted therapies and understanding peptide interactions with cancer cells.

Development & Formulation Notes

Reconstitution & Handling
For research purposes, reconstitute Tyrosylleucine in sterile water, PBS, or appropriate buffer at concentrations suitable for your experiments. When preparing solutions for use in cell cultures or enzyme assays, ensure proper sterile techniques and avoid contamination. Store reconstituted solutions at 4 °C for short-term use, and freeze aliquots for long-term storage to maintain peptide integrity.

Assay Design
For peptide synthesis applications, determine the optimal concentration of Tyrosylleucine based on the specific synthesis process you are using. It is recommended to perform small-scale tests to confirm the optimal molar ratio with other amino acids or peptide precursors.

Disclaimer

Tyrosylleucine is strictly for laboratory research use only. It is not a pharmaceutical, medical device, or diagnostic product and is not intended for human or veterinary applications. Always handle the product following biosafety protocols and use appropriate personal protective equipment (PPE). Dispose of any material in accordance with local safety regulations. Users are responsible for ensuring that the product is suitable for their specific research and for complying with all relevant laws and guidelines.

Packaging & Availability

Tyrosylleucine is available in the following packaging options:

• Standard Packs: 1 mg, 5 mg, 10 mg – ideal for research labs with smaller-scale needs.

• Bulk/Wholesale: Multi-gram quantities for larger research programs or institutional needs.
  Each lot includes a Certificate of Analysis (CoA) detailing the product’s purity, identity, and endotoxin levels, among other specifications.

Quality Assurance

Manufactured under GMP-compliant conditions, Tyrosylleucine undergoes rigorous testing for identity (MS), purity (HPLC), and endotoxin levels. Additional quality control measures are in place to ensure product consistency across batches. For research institutions or regulatory compliance, optional documentation is available upon request.

Custom Services

We offer the following custom services to support your research needs:

• Custom Aliquots & Labeling: Tailor packaging and labeling for specific requirements, including lot traceability.

• Peptide Synthesis Support: Assist with the design and synthesis of custom peptides using Tyrosylleucine as a building block.

• Stability Testing: Design and conduct stability studies to assess the long-term storage conditions for Tyrosylleucine and related compounds.

Keywords

Tyrosylleucine; Tyrosyl-Leu; dipeptide synthesis; peptide synthesis; amino acid research; GMP peptide; CAS 17355-10-1; research-use-only peptide; enzyme activity studies; protein folding research; drug discovery peptide.