Vorumotide (CAS 935395-34-9)

描述

Product Description

Vorumotide (CAS 935395-34-9) is a synthetic immunological peptide developed as an active immunization agent with antineoplastic properties. Its design enables researchers to explore both immune system activation and tumor growth inhibition in preclinical models.

Background and Significance

Immune system modulation plays a crucial role in controlling tumor development. Vorumotide functions as an immunostimulatory agent, enhancing antigen presentation, activating cytotoxic T cells, and promoting cytokine secretion. This makes it an invaluable research tool for:

• Studying cancer immunotherapy mechanisms.

• Exploring peptide-based vaccine development.

• Investigating immune modulation in oncology.

Preclinical studies indicate that Vorumotide can induce specific antitumor immune responses while maintaining a favorable safety profile in laboratory models. It is particularly suitable for studies involving tumor-bearing rodents, humanized immune system models, and in vitro immune assays.

Chemical Properties and Structure

• Compound Class: Synthetic immunological peptide

• Target: Immune system activation for antitumor responses

• Mechanism: Stimulates T cell and antigen-presenting cell activity

• Activity: Immunostimulatory, antineoplastic

• Stability: Lyophilized peptide ensures extended shelf life

• Applications: Tumor immunology, immune response studies, preclinical cancer research

Vorumotide’s synthetic design ensures high reproducibility and structural integrity, providing consistent biological activity across experimental batches.

Product Specifications

The specifications of Vorumotide ensure high purity, reproducibility, and reliable immunostimulatory activity, making it suitable for mechanistic and preclinical studies.

Mechanism of Action & Research Applications

Mechanism of Action

Vorumotide functions as an immunological and antineoplastic agent through several mechanisms:

1. Activation of Antigen-Presenting Cells (APCs): Stimulates dendritic cells and macrophages to enhance antigen presentation.

2. Cytotoxic T Cell Activation: Promotes CD8+ T cell proliferation and cytotoxic activity against tumor cells.

3. Cytokine Modulation: Induces secretion of interferons, interleukins, and other immunostimulatory cytokines.

4. Tumor Growth Inhibition: Enhances immune-mediated apoptosis in tumor cells and suppresses tumor progression in preclinical models.

This multi-faceted mechanism allows researchers to study both adaptive immune responses and direct antitumor effects.

Research Applications

1. Cancer Immunotherapy Research
Vorumotide is widely used to investigate peptide-based cancer vaccines and immune activation strategies.

2. Immune Activation Studies
Facilitates research into T cell, NK cell, and APC activation in controlled laboratory settings.

3. Cytokine Response Analysis
Used to profile immune signaling pathways and cytokine networks in response to peptide stimulation.

4. Preclinical Tumor Models
Suitable for rodent tumor models, humanized immune system mice, and ex vivo tumor-immune co-culture assays.

5. Combination Therapy Research
Supports studies combining immunostimulatory peptides with chemotherapy, checkpoint inhibitors, or other antitumor agents.

6. Translational Research
Data generated with Vorumotide informs the design of peptide-based immunotherapies and potential clinical strategies.

7. Mechanistic Immunology
Allows exploration of antigen presentation, immune cell trafficking, T cell receptor signaling, and immune tolerance mechanisms.

8. In Vitro Immune Profiling
Applicable to assays measuring T cell proliferation, cytokine secretion, and immune cell activation markers.

9. Comparative Immunotherapy Studies
Enables side-by-side evaluation with other immunostimulatory peptides to optimize efficacy and specificity.

10. Therapeutic Peptide Development
Vorumotide serves as a model for designing next-generation immunomodulatory peptides with enhanced potency and stability.

The versatility of Vorumotide in tumor immunology and immune modulation makes it a critical tool for research laboratories.

Side Effects (For Reference in Research Models)

Observations in preclinical studies include:

• Cytokine Release: Dose-dependent stimulation may induce transient cytokine elevations.

• Immune Cell Stress: High concentrations can temporarily stress certain immune cell populations.

• Species-Specific Responses: Effects vary across rodents, humanized mice, or ex vivo models.

• Peptide Stability Considerations: Repeated freeze-thaw cycles may reduce activity; proper storage is required.

• Tumor Model Variability: Immune response may differ depending on tumor type, stage, and immune status.

• Combination Effects: Interactions with other agents may alter immune activation or antitumor efficacy.

These observations are strictly for laboratory research reference. Vorumotide is not for human or veterinary use.

Disclaimer

For laboratory research use only. Not for human or veterinary use.

Keywords

• Vorumotide CAS 935395-34-9

• Antineoplastic immunological peptide

• Active immunization research peptide

• GMP-grade Vorumotide

• Cancer immunotherapy research peptide

• Tumor immunology peptide

• Laboratory immune response modulator

• Synthetic immunostimulatory peptide

• Peptide vaccine research compound

• Research use only immunological agen