Description
Pamidronate Disodium Injection Description
Product name: Pamidronate disodium for injection
Packing specification: 15mg*10 bottles Product dosage form: injection ? Packing unit: box
Approval number: National medicine standard H20093151 Drug standard code: 86902066001833
Manufacturer: Chengdu Tiantaishan Pharmaceutical Co., Ltd.
Pamidronate Disodium (pamidronic acid) is a second-generation nitrogen-containing bisphosphonate clinically used to prevent bone loss, treat osteoporosis, Paget’s disease, hypercalcemia of malignancy, and multiple myeloma-related bone disease?patents.google.com+12en.wikipedia.org+12prospectresearchreports.com+12.
This injection contains 15mg of active compound per vial, intended for intravenous infusion in research settings exploring:
Bone resorption and metabolism
Neoplastic bone lesions
Calcium homeostasis
Bisphosphonate-related side effects such as osteonecrosis of the jaw and hypocalcemia
Clinical pharmacokinetics show protein-binding ~54%, renal elimination, and a long half-life (~28±7h), making it suitable for steady-state dosing and mechanistic studies en.wikipedia.org.
Product Specifications
| Feature | Details |
|---|---|
| Product Name | Pamidronate Disodium Injection |
| Strength | 15mg pamidronate per vial |
| Quantity | 10 vials per box |
| Formulation | Sterile aqueous solution for IV infusion |
| Manufacturer | Chengdu Tiantai Shan Pharmaceutical Co., Ltd. |
| Approval Number (NMPA) | H20093151 |
| Product Code | 86902066001833 |
| Storage | Store at 2–8°C; protect from freeze and light |
| Shelf Life | 24 months (as per packaging) |
| Appearance | Clear, colorless solution |
| Administration Route | Intravenous infusion after dilution |
| Pharmacokinetics | Protein bound 54%, renal excretion, elimination half-life ~28h |
Mechanism of Action & Key Benefits
Bone preservation: Inhibits osteoclast-mediated bone resorption, reducing skeletal-related events.
Clinical relevance: Doses of 30–90mg monthly empower research in osteolytic conditions and hypercalcemia studies.
Rich pharmacokinetics: High protein binding and renal clearance favor predictable blood levels in models.
Side effect profiling: Common adverse reactions include fever, bone pain, hypocalcemia, and gastrointestinal upset—valuable for mechanistic toxicity research.
Why Choose This Product?
Approved and traceable by NMPA
Pharma-grade single-dose vials for convenient use
Supports robust research in bone disease, oncology, and metabolism
Ideal for chronic dosing or pharmacokinetic investigations
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Summary
Pamidronate Disodium 15mg Injection by Chengdu Tiantai Shan Pharma is a reliable research-grade tool for bone metabolism, oncology, and calcium homeostasis studies. With high-quality manufacture, clear pharmacokinetic profile, and injectable format, it’s suitable for a variety of lab models.


mamr –
Not bad, thank you