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Rilertinib mesylate (Sanrisso®), developed by Nanjing Sanhome Pharmaceutical Co., Ltd., is a third-generation EGFR-TKI approved by China’s NMPA (Approval No. H20240020; Drug Code: 86901583000930). Each bottle contains 20 tablets of 100?mg each. Strictly for laboratory research use only—not for clinical or human use.
| Attribute | Details |
|---|---|
| Product Name | Rilertinib Mesylate Tablets (Sanrisso®) |
| Dosage | 100?mg per tablet × 20 tablets per bottle |
| Formulation | Oral film-coated tablet |
| Approval No. | China NMPA H20240020 |
| Drug Code | 86901583000930 |
| Manufacturer | Nanjing Sanhome Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research only—Not for human or veterinary use |
Rilertinib mesylate (Sanrisso®) is a third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that targets activating mutations and the T790M resistance mutation in non-small cell lung cancer (NSCLC). It exhibits potent anti-tumor activity against EGFR-mutant NSCLC cell lines and tumor models.
China NMPA Approval (Feb 2025): Approved for patients with EGFR T790M mutation-positive advanced or metastatic NSCLC after progression on prior EGFR-TKI therapy.
Phase III Trials: Demonstrated superior progression-free survival (PFS) compared to gefitinib in EGFR-mutant NSCLC patients.
Ideal for:
EGFR pathway and T790M-resistance mechanisms
In vitro and in vivo NSCLC models
Drug resistance and combination therapy studies
Pharmacokinetic and pharmacodynamic profiling
Storage: Store at 20–25?°C, sealed and protected from light and moisture.
Handling: Use appropriate laboratory personal protective equipment (PPE); avoid ingestion or inhalation.
NMPA approval announcement (Feb 19, 2025)
Phase III trial results comparing rilertinib vs gefitinib
Drug mechanism and development synopsis
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 26 × 25 × 26 厘米 |
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tinknocke –
The logistics was very fast, I received it in 8 days