Drotaverine Hydrochloride 40?mg ×?5 Vials Wholesale price comparison

Drotaverine Hydrochloride 40?mg ×?5 Vials Wholesale price comparison

$2.00

Drotaverine is a spasmolytic PDE4 inhibitor used in preclinical research to relieve smooth muscle spasms—gastrointestinal, biliary, urinary, and uterine. Each vial contains 40?mg in 2?mL solution. Manufactured by Chongqing Shenghuaxi Pharmaceutical Co., Ltd., approved under NMPA H20183353, product code 86909568000197, barcode 6933982500616.
?? For laboratory research use only.?Please consult the staff for other purposes?

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Description

Product Specifications

AttributeDetails
Product NameDrotaverine Hydrochloride Injection
Generic NameDrotaverine Hydrochloride
CAS Number985?12?6 
Molecular FormulaC??H??NO? · HCl
Molecular Weight~433.97?g/mol
Dosage FormSolution for IM/IV injection
Strength40?mg per 2?mL vial
Pack Size5 vials per box
Approval No.H20183353 (China NMPA)
Product Code86909568000197
ManufacturerChongqing Shenghuaxi Pharmaceutical Co., Ltd.
Barcode6933982500616
StorageStore at 2–8?°C, protect from light
Intended UseLaboratory research use only

Mechanism of Action

Drotaverine selectively inhibits phosphodiesterase?4 (PDE4) and blocks L-type calcium channels, leading to smooth muscle relaxation without anticholinergic side effects. Useful in studies involving colic, dysmenorrhea, and uterine dilation.


Research Applications & Pharmacology

  • Smooth muscle spasm models: Effective in gastrointestinal, genitourinary, biliary, and uterine muscle studies (e.g., labor augmentation, renal colic relief)?go.drugbank.com.

  • Pharmacokinetics: High bioavailability (~65%), peak effect in 45–60 min, long half-life (7–16?hrs), 95–98% protein bound, hepatic elimination, urinary and biliary excretion?medchemexpress.com+2en.wikipedia.org+2clinicaltrials.gov+2.


Safety Profile & Handling

Adverse Effects:

  • Possible dizziness, headache, flushing, hypotension, tachycardia, rare arrhythmia/anaphylaxis.

  • Overdose can lead to AV block, respiratory depression, seizures, cardiac arrest.

Handling Guidelines:

  • Use PPE, aseptic technique.

  • Administer slowly via IM/IV; aspirate to avoid intravascular injection.

  • Monitor animals for cardiovascular and CNS responses.

  • Dispose of vials as pharmaceutical waste.


?? Research?Use Disclaimer

This product is intended solely for laboratory research and not approved for diagnosis, therapy, clinical, or veterinary use. Misuse may cause safety hazards and compromise scientific data.

Additional information

Weight1.1 kg
Dimensions18 × 16 × 18 cm

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