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Dutasteride Soft Capsules 0.5mg ×10 Capsules
Original price was: $53.00.$42.00Current price is: $42.00.
Dutasteride is a dual 5-reductase inhibitor that suppresses both type I and II enzymes, reducing dihydrotestosterone (DHT) levels by up to 98%. Supplied in 0.5mg soft gelatin capsules (10 per pack) by Jiangsu Wangao Pharmaceuticals, this product is intended exclusively for laboratory and preclinical research, including androgen suppression, BPH, and alopecia models. Not approved for clinical, therapeutic, diagnostic, or veterinary use.?Please consult staff for other specifications and uses
Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Dutasteride Soft Capsules |
| Generic Name | Dutasteride |
| CAS Number | 164656-23-9 |
| Molecular Formula | C27H30F6N2O2 |
| Molecular Weight | 528.53 g/mol |
| Dosage Form | Oral soft gelatin capsule |
| Strength | 0.5 mg per capsule |
| Pack Size | 10 capsules per box |
| Approval No. | China NMPA H20234210 |
| Product Code | 86901503000569 |
| Manufacturer | Jiangsu Wangao Pharmaceutical Co., Ltd. |
| Barcode | 6938033202990 |
| Storage Conditions | Store at 2–8°C or 15–25°C; protect from light |
| Intended Use | Laboratory/preclinical research only |
Mechanism of Action
Dutasteride is an irreversible inhibitor of both type I and II 5-reductase enzymes, preventing conversion of testosterone to DHT. It reduces serum DHT levels by up to 98%, significantly more than finasteride (~65–70%) .
Research Applications & Pharmacology
Benign Prostatic Hyperplasia (BPH) Models: Widely used to study prostate volume reduction and LUTS in preclinical contexts .
Androgenetic Alopecia (AGA) Models: More effective than finasteride in hair growth studies, especially at 0.5mg dosing .
Pharmacokinetics: Oral bioavailability ~60%, protein binding ~99%, metabolized via CYP3A4, elimination half-life ~4–5 weeks, mainly excreted in feces (~40%) .
Research Formulation Impact: Soft gelatin capsules offer higher bioavailability than tablets or hard capsules .
Safety Profile & Handling
Adverse Effects: Can cause sexual dysfunction, breast tenderness/gynecomastia (~1.3%), depression, and self-harm risks in long-term or high-dose models.
Drug Interactions/Contraindications: Avoid use in models with CYP3A4 inhibitors; contraindicated in female and pregnant subjects due to teratogenic risk .
Handling Instructions: Wear lab-safe PPE. Store per label instructions. Dispose of per institutional safety protocols.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
What is Dutasteride used for in research?
Dutasteride is commonly used in laboratory studies focusing on androgen metabolism, enzyme inhibition, and endocrine signaling pathways.
What enzyme does Dutasteride inhibit?
Dutasteride inhibits both type I and type II 5-alpha reductase enzymes, which convert testosterone into dihydrotestosterone (DHT).
What purity level is provided?
The active pharmaceutical ingredient is manufactured with ≥99% purity, verified by analytical testing methods.
What is the capsule strength?
Each soft capsule contains 0.5 mg of Dutasteride.
How should the product be stored?
The capsules should be stored below 25°C, protected from light and moisture.
What analytical methods verify the compound?
Identity and purity are confirmed using HPLC and mass spectrometry analysis.
Is this product intended for clinical use?
No. This product is supplied strictly for laboratory research purposes only.
Why is Dutasteride useful in endocrine research?
Because it strongly suppresses DHT formation, dutasteride helps researchers investigate androgen-dependent biological pathways and hormone regulation mechanisms.
What research areas commonly study Dutasteride?
Common fields include endocrinology, dermatology research, pharmacology, and urological biology studies.
Does Dutasteride dissolve in water?
No. Dutasteride is poorly soluble in water but dissolves in certain organic solvents used in laboratory settings.
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