Description

Adalimumab is a fully human monoclonal antibody targeting tumor necrosis factor?? (TNF??), a key cytokine in inflammatory and autoimmune pathways. Sulinnuo® is Xinda Biopharma’s domestically produced biosimilar equivalent to Humira®, supplied in a 40?mg/0.8?ml prefilled syringe format for precise dosing.

The product is manufactured by Xinda Biopharma (Suzhou) and received Chinese NMPA approval S20200020. It is commonly utilized in research projects modeling rheumatoid arthritis, Crohn’s disease, psoriasis, and other TNF-mediated inflammation processes.

?? For laboratory research use only. Not intended for clinical, veterinary, or diagnostic use.

Adalimumab Injection Product Specifications

Adalimumab Injection Mechanism & Research Applications

Adalimumab selectively binds TNF??, neutralizing its pro-inflammatory effects and preventing receptor activation. Sulinnuo® is employed in research for:

• Autoimmune disease models (RA, Crohn’s, psoriasis, uveitis)

• Inflammatory signaling and cytokine cascade studies

• Comparative efficacy of biosimilars vs originators

• Preclinical evaluation of TNF?? blockade mechanisms

Adalimumab Injection Side Effects (Observed in Preclinical/Research Settings)

Based on clinical biosimilar data, research models may show:

• Increased susceptibility to infections (e.g. TB, fungal, bacterial)

• Infusion or injection site reactions (fever, chills, hypotension)

• Laboratory anomalies: elevated liver enzymes, cytopenias

• Autoimmune phenomena akin to lupus-like syndrome

• Rare risks: demyelinating events, lymphoma (high-dose/prolonged exposure)

Recommendation: Monitor immunological markers and animal health.

Safety & Handling

• Use Restriction: For laboratory research only

• PPE: Use gloves, lab coat, and safety eyewear

• Storage: Store at 2–8?°C, avoid freezing or direct light

• Preparation: Use aseptic technique during handling

• Disposal: Follow institutional biohazard guidelines

Core Keywords

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Research Use Disclaimer

This product is exclusively for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may result in health risks and regulatory penalties. Users must follow biosafety and chemical handling protocols as per institutional guidelines.