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Nicorandil for Injection 12mg – For Laboratory Research Use Only
$2.00
Nicorandil for Injection (Ruikexi) contains 12mg of nicorandil per vial, supplied as 4 vials per box. Manufactured by Beijing Sihuan Kebao Pharmaceutical. Approved under H20120069. For laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Nicorandil is a dual-action vasodilator that acts as both a potassium channel opener and nitrate donor. In research, it is widely utilized in cardiovascular pharmacology to simulate ischemic heart conditions and study myocardial protection and vasodilation mechanisms.
This product delivers 12mg nicorandil per vial, with 4 vials per box, manufactured by Beijing Sihuan Kebao Pharmaceutical Co., Ltd. under NMPA approval number H20120069. It is intended strictly for non-clinical laboratory use.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Nicorandil for Injection (Ruikexi) |
| Active Ingredient | Nicorandil |
| CAS Number | 65141-46-0 |
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.18 g/mol |
| Dosage Form | Injection (Powder for Reconstitution) |
| Strength | 12mg per vial |
| Packaging | 4 vials per box |
| Approval Number | H20120069 (China NMPA) |
| Product Code | 86900151000945 |
| Manufacturer | Beijing Sihuan Kebao Pharmaceutical Co., Ltd. |
| Barcode | 6940146004026 |
| Intended Use | Laboratory research only |
| Storage Conditions | Store in a cool, dry place below 25°C |
Mechanism of Action & Research Applications
Nicorandil combines the properties of nitrate-like vasodilation and ATP-sensitive potassium channel activation. It causes relaxation of vascular smooth muscles, improves coronary blood flow, and reduces cardiac preload and afterload.
Research Applications:
Myocardial ischemia and reperfusion models
Vasodilation and endothelial response studies
Angina mechanism simulations
Comparative studies with nitrates and K-ATP openers
Evaluation of cardioprotective agents
Potential Side Effects in Research Models
Hypotension
Headache
Flushing
Gastrointestinal discomfort in high-dose models
Handling & Safety Information
Use Restriction: For laboratory research only.
Protective Equipment: Lab coat, gloves, and safety glasses recommended.
Storage: Keep below 25°C, away from moisture and light.
Disposal: Dispose of in accordance with institutional and environmental safety regulations.
Research Use Disclaimer
This product is provided strictly for laboratory research and is not intended for human or veterinary use. Misuse may result in regulatory or safety consequences. Handle only in certified research environments following proper protocols.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 42 × 23 × 42 cm |
Q1: Is this product approved for clinical use?
A1: No, it is intended strictly for non-human laboratory research.
Q2: Can this be ordered in bulk?
A2: Yes, we support both wholesale and retail orders. Contact us for bulk pricing.
Q3: Is this the same formulation used for angina?
A3: It contains the same active compound, but this version is designated for research purposes only, not clinical use.
Q4: Are SDS and COA documents provided?
A4: Yes, Certificate of Analysis (COA) and Safety Data Sheet (SDS) are available upon request.
Q5: How is it administered in research studies?
A5: Typically used via intravenous injection following reconstitution, as per lab protocols.
Q6: What does “Ruikexi” refer to?
A6: “Ruikexi” is the commercial brand name used by the manufacturer, Beijing Sihuan Kebao.
Q7: What studies is nicorandil most commonly used in?
A7: It is widely used in myocardial ischemia models, vasodilation research, and cardiac drug interaction studies.
Q8: How stable is this compound?
A8: When stored properly, it maintains integrity under recommended conditions. Reconstituted solutions should be used promptly.
Q9: What is the NMPA approval number?
A9: The approval number is H20120069, issued by the China NMPA.
Q10: Can I combine this with other cardiovascular agents for interaction studies?
A10: Yes, it is often used in combination studies with beta-blockers, nitrates, or calcium channel blockers in non-clinical settings.
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