Dynorphin A (CAS?80448?90?4) – Purity 95.18% | GMP Factory

Dynorphin A (CAS?80448?90?4) – Purity 95.18% | GMP Factory

$2.00

Dynorphin A is an endogenous opioid peptide with high affinity for ?-opioid receptors (KOR). Supplied in GMP-quality powder form at ?95.18% purity—ideal for neuropharmacology, pain, mood, and stress mechanism studies. Laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?

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描述

Dynorphin A (also referred to as dynorphin?(1–17)) is a naturally occurring opioid peptide derived from prodynorphin. It functions as a high-potency agonist at ?-opioid receptors (KOR), with greater selectivity over mu (MOR) and delta (DOR) opioid receptors. As an endogenous neuropeptide, Dynorphin A plays critical roles in pain modulation, mood regulation, stress response, and neural plasticity.

This GMP-manufactured, research-grade product offers reliable reproducibility with a purity of ?95.18%. It’s perfect for advanced studies in opioid signaling pathways, addiction mechanisms, and neuroinflammation.

For laboratory research use only. Not for clinical, therapeutic, or veterinary use.


Product Specifications

Feature Detail
Product Name Dynorphin A
CAS Number 80448?90?4
Purity ?95.18% (HPLC)
Molecular Weight ~2147.5 Da
Molecular Formula C??H???N??O??
Peptide Sequence Tyr–Gly–Gly–Phe–Leu–Arg–Arg–Ile–Arg–Pro–Lys–Leu–Lys–Trp–Asp–Asn–Gln
Appearance White to off-white lyophilized powder
Solubility Soluble in water (~0.8 mg/mL)
Storage Conditions ?20?°C, protect from light and moisture
Manufacturing GMP-compliant facility
Intended Use Laboratory research only

Mechanism of Action & Research Applications

Dynorphin A is a highly potent ?-opioid receptor (KOR) agonist; it also exhibits lower affinity for ? and ? opioid receptors. It plays fundamental roles in:

  • Modulating pain pathways in the central nervous system

  • Regulating mood, emotional behaviors, and stress responses

  • Influencing synaptic plasticity, such as inhibition of long-term potentiation in hippocampal circuits

This makes it invaluable for research in neuropharmacology, pain physiology, addiction, mood disorders, and neurodegeneration.


Side Effects (Research Context Only)

In experimental models, Dynorphin A may lead to:

  • KOR-mediated analgesia, dysphoria, or altered emotional states

  • Modulation of neurotransmitter release, including dopamine

  • Changes in synaptic strength or plasticity in neural circuits

These outcomes are context-dependent and observed in nonclinical laboratory studies.


Disclaimer

This product is intended strictly for laboratory research use only. It is not intended for human or veterinary use, diagnosis, or treatment. Use must comply with appropriate institutional and legal protocols.

其他信息

重量 1 公斤
尺寸 26 × 23 × 26 厘米

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