Description
Elamipretide Triacetate is a mitochondria-targeted tetrapeptide that selectively targets cardiolipin on the inner mitochondrial membrane. By stabilizing cardiolipin and improving mitochondrial bioenergetics, Elamipretide helps reduce mitochondrial dysfunction and oxidative damage. This compound is widely studied in experimental models of mitochondrial diseases, cardiovascular disorders, neurodegeneration, and metabolic syndromes.
Elamipretide Triacetate holds promise in research focused on improving mitochondrial health and mitigating the effects of mitochondrial-related cellular damage.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Elamipretide Triacetate |
| CAS Number | 1849610-71-4 |
| Purity | 99.76% (HPLC) |
| Molecular Formula | C41H68N10O7 |
| Molecular Weight | Approx. 830.04 Da |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water and aqueous buffers |
| Storage | Store at –20°C, protect from light and moisture |
| GMP Compliance | Yes |
| Intended Use | Laboratory research only |
Mechanism of Action & Research Applications
Elamipretide Triacetate selectively binds to cardiolipin in the inner mitochondrial membrane, stabilizing it and improving mitochondrial electron transport chain efficiency. This results in enhanced ATP production and reduced production of reactive oxygen species (ROS). Through this mechanism, Elamipretide helps prevent mitochondrial swelling, oxidative stress, and apoptosis in damaged cells.
Research applications include:
Studying mitochondrial dysfunction and bioenergetics
Investigating treatments for mitochondrial myopathies and cardiomyopathies
Exploring neurodegenerative disease mechanisms
Evaluating oxidative stress and cellular aging pathways
Side Effects (For Research Context Only)
In laboratory research, Elamipretide Triacetate has demonstrated low toxicity and good mitochondrial protective effects. Side effects in humans are not applicable as it is strictly for experimental use.
Disclaimer
Elamipretide Triacetate is intended solely for laboratory research use and is not approved for clinical or therapeutic applications.


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