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Abaloparatide – Purity 99.91% | GMP Factory
Original price was: $16.00.$14.00Current price is: $14.00.
Abaloparatide is a synthetic peptide analog of parathyroid hormone-related protein (PTHrP), acting as a selective parathyroid hormone receptor type 1 (PTH1R) agonist. It promotes bone formation and is widely used in osteoporosis-related research. Manufactured with 99.91% purity under GMP standards. Laboratory use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Abaloparatide is a 34-amino acid synthetic peptide designed to selectively activate PTH1R, stimulating bone formation and increasing bone mineral density. It mimics the effects of endogenous parathyroid hormone-related protein but with distinct receptor binding dynamics that favor anabolic effects on bone. This makes it a valuable molecule in the study of osteoporosis and related metabolic bone diseases. Abaloparatide research helps explore novel treatments for bone loss, fracture prevention, and skeletal regeneration.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Abaloparatide |
| Synonyms | BA058, Abaloparatide acetate (if applicable) |
| CAS Number | 247062-33-5 |
| Purity | 99.91% (HPLC) |
| Molecular Formula | C176H286N52O52 |
| Molecular Weight | Approx. 4115.87 Da |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water and aqueous buffers |
| Storage | –20°C, protect from light and moisture |
| GMP Compliance | Yes |
| Intended Use | Laboratory research only |
Mechanism of Action & Research Applications
Abaloparatide selectively binds to the parathyroid hormone receptor 1 (PTH1R), triggering signaling pathways that enhance osteoblast activity and bone formation. Its unique receptor binding profile results in rapid activation and internalization, promoting bone anabolism without significant resorption. This mechanism is critical in studying treatments for osteoporosis, fracture healing, and bone regenerative medicine.
Research applications include:
Osteoporosis disease models
Bone metabolism studies
Skeletal regeneration research
Evaluation of bone anabolic agents
Side Effects (For Research Context Only)
In laboratory models, abaloparatide may influence:
Bone remodeling markers
Cellular proliferation of osteoblasts
Calcium metabolism in experimental systems
Disclaimer
is intended solely for laboratory research use and is not approved for diagnostic, therapeutic, or clinical use.
Additional information
| Weight | 0.8 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
1 review for Abaloparatide – Purity 99.91% | GMP Factory
What is Abaloparatide?
Abaloparatide is a synthetic peptide and selective parathyroid hormone receptor type 1 (PTH1R) agonist used in bone research.
What is the CAS number of Abaloparatide?
The CAS number is 247062-33-5.
How does Abaloparatide work?
It binds to PTH1R receptors, stimulating bone formation and increasing bone density.
What research areas utilize Abaloparatide?
It is primarily used in osteoporosis, bone metabolism, and regenerative medicine research.
Is Abaloparatide produced under GMP standards?
Yes, this product is manufactured in a GMP-compliant facility.
What purity level does Abaloparatide have?
The purity is 99.91%.
How should Abaloparatide be stored?
Store at –20°C, protected from light and moisture.
Can Abaloparatide be used clinically?
No, it is strictly for laboratory research use only.
What are the key benefits of Abaloparatide in research?
It offers targeted stimulation of bone formation, useful for studying therapies against osteoporosis.
Why is Abaloparatide important in bone research?
Because of its selective receptor activity and potent anabolic effects on bone, it helps develop new strategies for bone health management.
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