Abaloparatide – Purity 99.91% | GMP Factory

Abaloparatide – Purity 99.91% | GMP Factory

$2.00

Abaloparatide is a synthetic peptide analog of parathyroid hormone-related protein (PTHrP), acting as a selective parathyroid hormone receptor type 1 (PTH1R) agonist. It promotes bone formation and is widely used in osteoporosis-related research. Manufactured with 99.91% purity under GMP standards. Laboratory use only.?For wholesale prices, other specifications and uses, please consult our staff?

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描述

Abaloparatide is a 34-amino acid synthetic peptide designed to selectively activate PTH1R, stimulating bone formation and increasing bone mineral density. It mimics the effects of endogenous parathyroid hormone-related protein but with distinct receptor binding dynamics that favor anabolic effects on bone. This makes it a valuable molecule in the study of osteoporosis and related metabolic bone diseases. Abaloparatide research helps explore novel treatments for bone loss, fracture prevention, and skeletal regeneration.


Product Specifications

Parameter Details
Product Name Abaloparatide
Synonyms BA058, Abaloparatide acetate (if applicable)
CAS Number 247062-33-5
Purity 99.91% (HPLC)
Molecular Formula C176H286N52O52
Molecular Weight Approx. 4115.87 Da
Appearance White to off-white lyophilized powder
Solubility Soluble in water and aqueous buffers
Storage –20°C, protect from light and moisture
GMP Compliance Yes
Intended Use Laboratory research only

Mechanism of Action & Research Applications

Abaloparatide selectively binds to the parathyroid hormone receptor 1 (PTH1R), triggering signaling pathways that enhance osteoblast activity and bone formation. Its unique receptor binding profile results in rapid activation and internalization, promoting bone anabolism without significant resorption. This mechanism is critical in studying treatments for osteoporosis, fracture healing, and bone regenerative medicine.

Research applications include:

  • Osteoporosis disease models

  • Bone metabolism studies

  • Skeletal regeneration research

  • Evaluation of bone anabolic agents


Side Effects (For Research Context Only)

In laboratory models, abaloparatide may influence:

  • Bone remodeling markers

  • Cellular proliferation of osteoblasts

  • Calcium metabolism in experimental systems


Disclaimer

is intended solely for laboratory research use and is not approved for diagnostic, therapeutic, or clinical use.

其他信息

重量 0.8 公斤
尺寸 26 × 23 × 26 厘米

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What is Abaloparatide?

Abaloparatide is a synthetic peptide and selective parathyroid hormone receptor type 1 (PTH1R) agonist used in bone research.

What is the CAS number of Abaloparatide?

The CAS number is 247062-33-5.

How does Abaloparatide work?

It binds to PTH1R receptors, stimulating bone formation and increasing bone density.

What research areas utilize Abaloparatide?

It is primarily used in osteoporosis, bone metabolism, and regenerative medicine research.

Is Abaloparatide produced under GMP standards?

Yes, this product is manufactured in a GMP-compliant facility.

What purity level does Abaloparatide have?

The purity is 99.91%.

How should Abaloparatide be stored?

Store at –20°C, protected from light and moisture.

Can Abaloparatide be used clinically?

No, it is strictly for laboratory research use only.

What are the key benefits of Abaloparatide in research?

It offers targeted stimulation of bone formation, useful for studying therapies against osteoporosis.

Why is Abaloparatide important in bone research?

Because of its selective receptor activity and potent anabolic effects on bone, it helps develop new strategies for bone health management.


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