Abarelix (CAS 183552-38-7) – GMP Manufacturer

Abarelix (CAS 183552-38-7) – GMP Manufacturer

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Abarelix is a synthetic GnRH antagonist (purity ?99.90%), manufactured under GMP conditions. It inhibits gonadotropin secretion by binding to GnRH receptors, used in prostate cancer research. Available for wholesale and retail; for laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?

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Description

Abarelix (CAS 183552-38-7) is a synthetic decapeptide and a potent gonadotropin-releasing hormone (GnRH) antagonist. It functions by binding to and blocking the GnRH receptor in the anterior pituitary gland, inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This suppression leads to a decrease in testosterone production, which is crucial for the growth of hormone-sensitive prostate cancer cells. Abarelix is utilized in research to study its effects on hormone regulation and prostate cancer treatment mechanisms. Synthesized under GMP conditions with a purity of ?99.90%, it ensures high-quality material for pharmaceutical and biochemical research.


Product Specifications

ParameterDetails
Product NameAbarelix
SynonymsPPI-149, R3827
CAS No.183552-38-7
Purity?99.90%
Molecular FormulaC??H??ClN??O??
Molecular Weight1416.10 Da
AppearanceWhite to off-white powder
SolubilitySoluble in water and DMSO
Storage ConditionsStore at –20?°C; protect from light and moisture
Manufacturing StandardGMP-compliant
ApplicationsProstate cancer research, hormone regulation studies
Regulatory StatusFor laboratory research use only

Mechanism of Action & Research Applications

Abarelix functions as a potent GnRH antagonist by binding to and blocking the GnRH receptor in the anterior pituitary gland. This action inhibits the secretion of LH and FSH, leading to a decrease in testosterone production. In prostate cancer research, this mechanism is crucial for studying hormone regulation and developing treatment strategies for hormone-sensitive cancers. Its high purity and GMP manufacturing ensure reliability in experimental settings.


Disclaimer

This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Please adhere to institutional safety protocols when handling.

Additional information

Weight1 kg
Dimensions36 × 38 × 36 cm

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