ABT-510 Acetate (CAS 442526-87-6) – High Purity 99.61%

ABT-510 Acetate (CAS 442526-87-6) – High Purity 99.61%

(1 customer review)

$2.00

ABT-510 Acetate is a GMP-grade TSP-1 mimetic peptide (purity ? 99.61%) that induces apoptosis in endothelial cells and inhibits angiogenesis. Available for both wholesale and retail. Laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?

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Description

ABT-510 Acetate is a synthetic nine-amino-acid peptide derived from the type 1 repeat of thrombospondin-1 (TSP-1). It mimics TSP-1’s anti-angiogenic function by binding to CD36 receptors, inducing apoptosis in microvessel endothelial cells, and inhibiting tumor neovascularization. Preclinical studies demonstrate its efficacy in reducing ovarian tumor growth, reducing microvessel density, and enhancing chemotherapy delivery via vascular normalization. Manufactured under GMP conditions with ? 99.61% purity.


Product Specifications

ParameterDetails
Product NameABT-510 Acetate
SynonymsABT-510; TSP-1 mimetic peptide
CAS No.442526-87-6
Purity? 99.61% (GMP-grade)
Molecular FormulaC??H??N??O??
Molecular Weight~1054.28 Da
AppearanceWhite to off-white solid
SolubilitySoluble in water (up to 100 mg/mL with sonication); compatible with DMSO
Storage ConditionsStore at –20 °C, dry and light-protected
Manufacturing StandardGMP-compliant
ApplicationsAnti-angiogenesis research, tumor and inflammation models
Regulatory StatusFor laboratory research use only

Mechanism of Action & Research Applications

ABT-510 Acetate mimics TSP-1 by binding to CD36 receptors on endothelial cells, triggering caspase-8-dependent apoptosis and inhibiting vascular tube formation. It has demonstrated potent anti-angiogenic effects, tumor growth inhibition, and reduced inflammation in preclinical models including ovarian cancer and inflammatory bowel disease.


Disclaimer

This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handle in accordance with institutional safety protocols.

Additional information

Weight1 kg
Dimensions43 × 23 × 43 cm

1 review for ABT-510 Acetate (CAS 442526-87-6) – High Purity 99.61%

  1. Bioth

    The sales team communicated clearly

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What is ABT-510 Acetate?

ABT-510 Acetate is a synthetic TSP-1 mimetic peptide with powerful anti-angiogenic and pro-apoptotic activity in endothelial cells.

What receptor does ABT-510 Acetate target?

It engages CD36 receptors on endothelial cells, initiating apoptosis and blocking blood vessel formation.

What purity level is guaranteed?

The product is highly pure, at least 99.61%, and manufactured under GMP guidelines.

How effective is ABT-510 Acetate in research models?

It reduces tumor growth, lowers microvessel density, and decreases inflammation in preclinical models such as ovarian cancer and inflammatory bowel disease.

What are common research applications?

Used in studies on tumor angiogenesis, vascular remodeling, combination therapies, and inflammatory disease modeling.

How soluble is ABT-510 Acetate and how should it be stored?

Soluble in water up to ~100 mg/mL with ultrasonic assistance, and also compatible with DMSO. Store as a dry powder at –20 °C, protected from light and moisture.

Can ABT-510 Acetate be used clinically?

No, this product is strictly for laboratory research use and is not approved for human or veterinary applications.

Is wholesale availability supported?

Yes, ABT-510 Acetate is available in both retail and wholesale quantities, complete with GMP documentation upon request.


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