Description

Product Description

Acetyl decapeptide-3 is a chemically synthesized bioactive peptide composed of ten amino acids, modified with an acetyl group to increase stability and skin penetration. It is widely studied in cosmetic and dermatological research for its ability to combat skin aging and promote facial rejuvenation. With a CAS number of 935288-50-9, this peptide has become a reference compound in laboratory research on anti-aging cosmetic formulations.

This peptide functions by modulating the activity of dermal fibroblasts, stimulating the production of extracellular matrix proteins such as collagen, elastin, and fibronectin. By enhancing collagen deposition, Acetyl decapeptide-3 contributes to increased skin density, elasticity, and overall firmness, which are critical factors in reducing wrinkle depth and visible signs of aging. Its effects have been demonstrated in in vitro and ex vivo models where fibroblast proliferation and matrix protein synthesis were significantly enhanced.

Acetyl decapeptide-3 also exhibits antioxidant properties, protecting skin cells from reactive oxygen species (ROS)-induced damage, a major contributor to photoaging. The peptide has been observed to mitigate oxidative stress, enhance cellular repair mechanisms, and improve tissue resilience under environmental stressors like UV radiation and pollution.

Beyond anti-aging, Acetyl decapeptide-3 has been explored for its synergistic effects when combined with other cosmetic peptides, enhancing the overall efficacy of anti-wrinkle and skin-rejuvenating formulations. It also helps preserve the extracellular matrix by downregulating matrix metalloproteinases (MMPs), enzymes responsible for collagen degradation, ensuring longer-lasting structural integrity in the skin.

Its small molecular size and acetylation allow for effective skin penetration, making it suitable for topical application research in laboratory models. Researchers can investigate its effects on signaling pathways, fibroblast activity, and extracellular matrix dynamics, providing insights into cosmetic peptide therapeutics.

Product Specifications

Mechanism of Action

Acetyl decapeptide-3 functions primarily by modulating fibroblast activity and extracellular matrix composition:

1. Collagen Stimulation:
   It promotes type I and III collagen production, improving dermal density and skin firmness.

2. Elastin and Fibronectin Production:
   The peptide increases elastin and fibronectin synthesis, enhancing skin elasticity and structural support.

3. Matrix Preservation:
   By inhibiting matrix metalloproteinases (MMPs), it reduces collagen degradation and slows wrinkle formation.

4. Antioxidant Protection:
   Acetyl decapeptide-3 mitigates oxidative stress, protecting fibroblasts from ROS-induced damage and supporting long-term skin health.

5. Cellular Repair and Renewal:
   It stimulates fibroblast proliferation and extracellular matrix organization, contributing to tissue repair and rejuvenation.

These mechanisms establish Acetyl decapeptide-3 as a potent tool in cosmetic peptide research, particularly in anti-aging studies, skin elasticity improvement, and wrinkle reduction assays.

Side Effects

Laboratory studies report that Acetyl decapeptide-3 exhibits excellent biocompatibility at standard experimental concentrations. No cytotoxic effects are observed. It is intended solely for research use, not for human or veterinary administration. Standard safety measures, such as sterile handling and personal protective equipment, should be followed during laboratory experiments.

Keywords

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Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.