Description
Product Description
Acetyl dipeptide-3 aminohexanoate is a short-chain synthetic peptide engineered to mimic endogenous dermal signaling molecules involved in skin regeneration. Its unique amino acid sequence allows it to interact with fibroblasts, regulating collagen and elastin production, enhancing extracellular matrix remodeling, and improving dermal structural integrity. Widely utilized in in vitro models, this peptide offers researchers a reliable tool for investigating anti-aging mechanisms, wrinkle reduction, and skin rejuvenation pathways.
Molecular Function and Bioactivity
The peptide acts as a signaling molecule that modulates fibroblast activity, upregulates collagen I and III expression, and promotes elastin and fibronectin synthesis. Its amphiphilic nature facilitates dermal penetration, making it suitable for laboratory studies on topical delivery, serum, and cream-based formulations.
Fibroblast Activation
Acetyl dipeptide-3 aminohexanoate stimulates fibroblast proliferation, migration, and extracellular matrix deposition. Laboratory results demonstrate increases in dermal density, elasticity, and resilience. The peptide’s ability to regulate fibroblast behavior is essential for research on collagen remodeling, wrinkle attenuation, and skin rejuvenation.
Extracellular Matrix Preservation
This peptide inhibits matrix metalloproteinases (MMP-1 and MMP-9), enzymes responsible for collagen and elastin degradation. By preserving the extracellular matrix, it maintains dermal integrity and supports anti-aging studies.
Synergistic Research Applications
Acetyl dipeptide-3 aminohexanoate is often studied in combination with other bioactive peptides, such as palmitoyl tripeptides or acetyl hexapeptides, to explore synergistic effects on collagen synthesis, dermal elasticity, and fibroblast activation. These combinatorial studies enable the development of multi-targeted peptide formulations for advanced anti-aging research.
Stability and Handling
Supplied as a lyophilized powder with ≥99% purity, the peptide is water-soluble and suitable for laboratory research. Stability is maintained under refrigerated conditions (2–8 °C) and protected from light and moisture. Proper handling ensures reproducible experimental outcomes.
Laboratory Research Applications
Acetyl dipeptide-3 aminohexanoate is applied in:
Human dermal fibroblast culture studies
Reconstructed human epidermal models
Collagen and elastin synthesis assays
Matrix metalloproteinase activity analysis
Fibroblast proliferation and migration studies
These models allow detailed investigation of peptide bioactivity, dermal regeneration pathways, and experimental cosmetic formulation efficacy.

Product Specifications
| Property | Specification |
|---|---|
| Product Name | Acetyl dipeptide-3 aminohexanoate |
| CAS Number | 1176133-78-0 |
| Synonyms | Acetyl Dipeptide-3, Acetyl-HexaPep-3 |
| Molecular Formula | C_20H_38N_6O_5 |
| Molecular Weight | 438.55 g/mol |
| Purity | ≥99% |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water and aqueous buffers; partial solubility in ethanol |
| Storage Temperature | 2–8 °C |
| Category | Cosmetic peptide |
| Applications | Anti-aging research, collagen synthesis, skin elasticity, fibroblast proliferation, cosmetic peptide studies |
| Formulation | Suitable for serum, cream, or cosmetic peptide research formulations |
| Stability | Stable under recommended storage conditions for ≥24 months |
| Analytical Verification | HPLC, MS, and NMR confirmed |
| Supplier Type | Factory peptide supplier |
| Intended Use | For laboratory research use only |
| Batch Analysis | Each batch supplied with a Certificate of Analysis (CoA) |
| Handling Notes | Avoid prolonged exposure to high temperature, UV light, and moisture; use standard laboratory PPE |
Mechanism of Action
Acetyl dipeptide-3 aminohexanoate enhances skin rejuvenation and anti-aging processes through fibroblast stimulation, collagen synthesis, and matrix protection.
Collagen Stimulation
Activates TGF-β/SMAD signaling to increase collagen type I and III production, improving dermal firmness and elasticity.Elastin Enhancement
Promotes elastin synthesis to increase dermal flexibility and resilience.Matrix Metalloproteinase Inhibition
Suppresses MMP-1 and MMP-9 activity, preserving collagen and elastin and preventing extracellular matrix degradation.Fibroblast Activation
Enhances fibroblast proliferation and migration, supporting matrix deposition and tissue repair.Anti-Inflammatory Modulation
Reduces pro-inflammatory cytokines (IL-6, TNF-α, COX-2), improving dermal regeneration conditions.Synergistic Peptide Research
Works with other bioactive peptides to improve collagen synthesis, matrix integrity, and anti-aging outcomes.
Side Effects
Intended solely for laboratory research. Observed effects show minimal cytotoxicity in vitro. Considerations include:
Perform preliminary concentration-dependent cytotoxicity assays.
Use compatible solvents; water and aqueous buffers recommended.
Store at 2–8 °C, protected from light and moisture.
Use standard laboratory PPE.
Not for human or veterinary administration.
Stable for ≥24 months under recommended storage conditions.
Keywords
Acetyl dipeptide-3 aminohexanoate, anti-aging peptide, skin rejuvenation, collagen stimulator, fibroblast regulator, cosmetic peptide, laboratory research peptide, high-purity peptide, peptide wholesale China, OEM peptide production, China peptide manufacturer
Shipping Guarantee
All Acetyl dipeptide-3 aminohexanoate shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.
Trade Assurance
We Acetyl dipeptide-3 aminohexanoate ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.
Payment Support
We Acetyl dipeptide-3 aminohexanoate provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.
Disclaimer
All Acetyl dipeptide-3 aminohexanoate products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.







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