Description

Product Description

Acetyl sh-heptapeptide-1 is a bioactive peptide composed of seven amino acids, chemically modified with an acetyl group to enhance stability and skin penetration. Assigned CAS number 1356845-72-1, this peptide has gained attention in cosmetic and dermatological research due to its anti-aging properties and potential in facial skin rejuvenation.

The peptide works by signaling dermal fibroblasts to stimulate the synthesis of extracellular matrix proteins, including collagen and elastin. These structural proteins are critical for maintaining skin elasticity, firmness, and smooth texture. Laboratory studies have shown that Acetyl sh-heptapeptide-1 can reduce wrinkle depth, enhance hydration, and improve overall dermal density, making it a valuable model compound in anti-aging peptide research.

Acetyl sh-heptapeptide-1 also exhibits protective effects against oxidative stress, a major factor in skin aging. By reducing reactive oxygen species (ROS) accumulation in dermal fibroblasts, it minimizes cellular damage caused by environmental stressors such as UV radiation and pollution. This antioxidant activity contributes to long-term skin health in experimental models.

Research applications of Acetyl sh-heptapeptide-1 extend to studying the modulation of collagen-degrading enzymes like matrix metalloproteinases (MMPs). The peptide has been shown to inhibit MMP activity, thereby preserving dermal matrix integrity. In combination with other cosmetic peptides, it can serve as a reference compound for synergistic anti-aging studies targeting wrinkle reduction, skin elasticity, and facial rejuvenation.

The peptide’s small molecular size, acetyl modification, and bioactive sequence make it suitable for topical delivery models, enabling investigation of skin absorption, penetration, and intracellular signaling pathways in cosmetic research.

Product Specifications

Mechanism of Action

Acetyl sh-heptapeptide-1 acts primarily through signaling pathways in dermal fibroblasts to stimulate collagen synthesis and reduce signs of skin aging. Upon entering the dermal microenvironment, it binds to specific receptors and triggers intracellular cascades that promote extracellular matrix protein production.

1. Collagen Synthesis:
   The peptide enhances type I and III collagen production, which increases dermal density and skin firmness.

2. Elastin Production:
   Elastin fibers, essential for skin elasticity and resilience, are upregulated, helping maintain smooth and supple skin.

3. Matrix Preservation:
   Acetyl sh-heptapeptide-1 inhibits matrix metalloproteinases (MMPs), preventing collagen degradation and slowing wrinkle formation.

4. Antioxidant Activity:
   By reducing reactive oxygen species (ROS), the peptide protects fibroblasts from oxidative damage, supporting long-term skin health.

5. Cellular Repair and Renewal:
   The peptide promotes fibroblast proliferation and extracellular matrix organization, contributing to enhanced tissue repair and regeneration.

Through these mechanisms, Acetyl sh-heptapeptide-1 serves as a robust model for studying cosmetic anti-aging interventions, facial skin rejuvenation, and peptide-based dermal therapies.

Side Effects

In laboratory research, Acetyl sh-heptapeptide-1 has demonstrated excellent biocompatibility. No cytotoxic effects are observed at standard experimental concentrations. The peptide should only be used for in vitro, ex vivo, or cosmetic peptide research studies. It is not intended for human or veterinary use.

Standard laboratory safety precautions apply, including handling under sterile conditions, using protective gloves, and minimizing repeated freeze–thaw cycles to preserve peptide stability.

Keywords

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Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Acetyl sh-heptapeptide-1 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Acetyl sh-heptapeptide-1 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Acetyl sh-heptapeptide-1 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.