Description

Product Description

Acetyl tetrapeptide-11 is a research-grade tetrapeptide designed for advanced cosmetic studies focusing on anti-aging and skin renewal mechanisms. As a biomimetic peptide, it emulates natural sequences involved in dermal matrix organization, helping restore structural protein balance in aging or photo-damaged skin. The compound has gained recognition for its ability to improve cohesion between dermal and epidermal layers, resulting in smoother, firmer, and more radiant skin appearance in laboratory studies.

From a biochemical standpoint, Acetyl tetrapeptide-11 interacts with cell-surface receptors on fibroblasts and keratinocytes, triggering pathways associated with extracellular matrix regeneration. It enhances the expression of integrins, fibronectin, and desmosomal proteins—critical components that strengthen cellular adhesion and tissue integrity. This effect supports improved skin density and resilience under repeated environmental stress or oxidative conditions.

Studies have also shown that Acetyl tetrapeptide-11 helps stimulate collagen types I and IV synthesis while modulating the production of elastin and fibrillin, leading to greater structural support in the dermis. This mechanism contributes to reduced wrinkle depth and enhanced elasticity, making it a promising molecule for anti-aging research formulations.

Moreover, Acetyl tetrapeptide-11 plays a key role in promoting epidermal renewal. It upregulates keratinocyte differentiation markers such as involucrin and filaggrin, supporting barrier repair and hydration retention. By reinforcing epidermal cohesion, this peptide ensures a smoother surface texture, contributing to visibly youthful skin in controlled test models.

Another advantage of Acetyl tetrapeptide-11 lies in its high biochemical stability due to acetyl modification, which enhances its resistance to enzymatic degradation and allows for prolonged activity in topical or in vitro environments. Researchers often combine it with other synergistic peptides, such as palmitoyl tripeptide-1 or acetyl hexapeptide-8, to target multiple aging pathways and improve overall skin matrix performance.

Overall, Acetyl tetrapeptide-11 serves as a multi-functional molecule that supports dermal remodeling, promotes skin elasticity, and contributes to age-defying cosmetic research. Its well-characterized structure and high purity make it ideal for formulation studies aiming to enhance barrier function, improve texture, and reduce visible signs of skin aging.

Product Specifications

Mechanism of Action

Acetyl tetrapeptide-11 exerts its effects through multiple biochemical mechanisms targeting both dermal and epidermal layers:

1. Enhancement of Extracellular Matrix Proteins

This peptide activates fibroblast pathways responsible for collagen and elastin synthesis. By stimulating TGF-β signaling and fibronectin gene expression, it increases dermal matrix density and supports skin firmness.

2. Stimulation of Keratinocyte Differentiation

Acetyl tetrapeptide-11 promotes the synthesis of epidermal differentiation proteins such as involucrin and keratin-10, essential for epidermal cohesion and barrier function. This action improves overall skin smoothness and hydration.

3. Regulation of Cellular Adhesion Molecules

Through modulation of integrin and desmosome-associated proteins, Acetyl tetrapeptide-11 strengthens the dermal-epidermal junction (DEJ). This structural reinforcement helps resist sagging and reduces visible wrinkles.

4. Protection Against Oxidative Stress

The peptide helps balance reactive oxygen species (ROS) levels by enhancing antioxidant defense enzymes within dermal fibroblasts. This protection minimizes oxidative damage associated with premature aging.

5. Synergistic Activity with Other Peptides

When combined with peptides such as palmitoyl tripeptide-5 or acetyl hexapeptide-37, Acetyl tetrapeptide-11 demonstrates complementary mechanisms—improving collagen cross-linking, hydration, and barrier strength simultaneously.

Side Effects

In laboratory conditions, Acetyl tetrapeptide-11 has shown a favorable safety profile with minimal cytotoxicity and no irritation in reconstructed human epidermal models. It is well tolerated under standard in vitro testing concentrations.

As with all peptide-based materials, variations in concentration, solvent system, or pH may influence results. It is recommended to perform concentration-dependent viability and compatibility tests during formulation research. The peptide should be stored at 2–8 °C and protected from moisture and direct light to preserve integrity.

Acetyl tetrapeptide-11 is intended exclusively for scientific and cosmetic research use. It is not suitable for human or animal administration.

Keywords

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Shipping Guarantee

All Acetyl tetrapeptide-11 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Acetyl tetrapeptide-11 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Acetyl tetrapeptide-11 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Acetyl tetrapeptide-11 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.