Description
Product Description
Acetyl tetrapeptide-22 is a bioactive tetrapeptide with proven efficacy in supporting skin repair and regeneration. As a peptide widely applied in cosmetic research, it functions by stimulating fibroblast activity, enhancing extracellular matrix (ECM) synthesis, and reinforcing skin structural integrity. This peptide promotes the formation of collagen and elastin fibers, improving skin elasticity and reducing visible signs of aging such as fine lines, wrinkles, and sagging.
Research indicates that Acetyl tetrapeptide-22 can activate repair pathways in dermal fibroblasts, aiding in the regeneration of damaged skin cells and mitigating the effects of photoaging. It also helps in regulating inflammatory responses within the skin, reducing oxidative stress, and promoting overall skin health. In addition to its anti-aging benefits, this peptide supports skin hydration, barrier function, and epidermal homeostasis, making it an ideal candidate for formulation into cosmetic creams, serums, and other topical applications aimed at skin rejuvenation.
By combining molecular precision and targeted action, Acetyl tetrapeptide-22 helps restore skin vitality, improve dermal density, and maintain youthful skin appearance. Its versatility allows it to be used synergistically with other bioactive compounds, including hyaluronic acid, vitamins, and other cosmetic peptides, to optimize skin repair outcomes.

Product Specifications
| Parameter | Specification |
|---|---|
| Product Name | Acetyl tetrapeptide-22 |
| CAS Number | 1295648-76-8 |
| Molecular Formula | C<sub>44</sub>H<sub>66</sub>N<sub>10</sub>O<sub>12</sub> |
| Molecular Weight | 902.05 g/mol |
| Appearance | White lyophilized powder |
| Purity | ≥99% |
| Storage Temperature | 2–8 °C |
| Solubility | Soluble in water or aqueous buffers |
| Applications | Skin repair research, anti-aging cosmetic studies |
| Synonyms | Acetyl-Tetrapeptide-22, Bioactive Tetrapeptide-22 |
Mechanism of Action
Acetyl tetrapeptide-22 acts primarily by stimulating fibroblast proliferation and enhancing extracellular matrix synthesis, including collagen types I and III and elastin fibers. By promoting ECM production, the peptide strengthens dermal architecture and supports the restoration of skin elasticity.
It also reduces matrix metalloproteinase (MMP) activity, which is responsible for collagen degradation during aging and photoexposure. Simultaneously, Acetyl tetrapeptide-22 exerts antioxidant activity by mitigating reactive oxygen species (ROS), reducing oxidative damage, and improving cellular resilience.
On a molecular level, Acetyl tetrapeptide-22 has been shown to modulate intracellular signaling pathways involved in cell repair and dermal regeneration. These effects collectively contribute to the peptide’s efficacy in repairing damaged skin, enhancing skin barrier function, and delaying the appearance of age-related skin changes.
The peptide can be integrated into cosmetic research focusing on anti-aging, photoprotection, and skin restoration. Its compatibility with other bioactive ingredients allows synergistic enhancement of skin rejuvenation formulations.

Side Effects
Acetyl tetrapeptide-22 is generally considered safe for research and cosmetic applications when used at recommended concentrations. Minimal cytotoxicity has been observed in fibroblast and keratinocyte cultures. As with all bioactive peptides, it should be handled according to institutional safety guidelines.
Keywords
Acetyl tetrapeptide-22, skin repair peptide, anti-aging peptide, collagen synthesis, fibroblast activator, cosmetic peptide research, high purity peptide
Shipping Guarantee
All Acetyl tetrapeptide-22 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.
Trade Assurance
We Acetyl tetrapeptide-22 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.
Payment Support
We Acetyl tetrapeptide-22 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.
Disclaimer
All Acetyl tetrapeptide-22 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.





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