Description

Product Description

Argipressin is a biologically active, high purity, factory manufactured peptide widely used in laboratory research for studying vasopressin receptor signaling, cardiovascular regulation, renal water balance, and neuroendocrine function. Supplied as a lyophilized powder, this peptide provides consistent and reproducible results across in vitro and in vivo experimental models. Its high purity formulation ensures minimal batch-to-batch variability, making it ideal for long-term studies, multi-phase research, and wholesale applications in research institutions.

This peptide functions as a selective agonist of vasopressin receptors, including V1a, V1b, and V2, allowing precise control of receptor-mediated pathways. In cardiovascular research, it facilitates the study of vasoconstriction, systemic vascular resistance, and blood pressure regulation. The factory manufactured quality ensures reproducible receptor activation, essential for mechanistic experiments, dose-response analyses, and comparative studies in preclinical models.

In renal physiology, the peptide modulates aquaporin-2 trafficking and sodium reabsorption in the collecting ducts, enabling researchers to investigate water homeostasis, urine concentration, and kidney function under both normal and experimental conditions. Neuroendocrine studies benefit from its ability to influence the hypothalamic-pituitary-adrenal (HPA) axis and adrenocorticotropic hormone (ACTH) release through V1b receptor activation, providing insight into stress response and hormonal regulation.

The high purity, factory manufactured peptide is compatible with diverse experimental systems, including primary cell cultures, organoid models, and rodent studies. It is also suitable for integration with multi-omic analyses and computational modeling, where reproducible receptor activation is critical. Its wholesale availability ensures a stable supply for large-scale experiments, multi-center collaborations, and extended research programs.

Reconstitution in sterile water, PBS, or appropriate buffers provides flexibility in experimental design. The peptide can be used in receptor binding assays, organ-specific physiological studies, and computational simulations. The lyophilized form maintains stability during long-term storage, ensuring consistent performance throughout extended studies.

In conclusion, this high purity, factory manufactured peptide combines selective receptor activity with reliable performance, making it an indispensable tool for cardiovascular, renal, and neuroendocrine research. Its wholesale availability guarantees reproducibility and dependable supply for advanced laboratory research, multi-omic studies, and translational applications.

Product Specifications

Mechanism of Action

Argipressin, a high purity, factory manufactured peptide, acts as a selective agonist of vasopressin receptors, including V1a, V1b, and V2, enabling precise regulation of cardiovascular, renal, and neuroendocrine functions. Binding to V1a receptors in vascular smooth muscle cells triggers vasoconstriction, increasing systemic vascular resistance and blood pressure. This property makes it a valuable tool for studying vascular tone and hemodynamic responses in experimental models.

Activation of V2 receptors in renal collecting ducts promotes aquaporin-2 insertion into the apical membrane, facilitating water reabsorption and urine concentration. This receptor-mediated mechanism is essential for investigating water homeostasis, electrolyte balance, and kidney function under both physiological and experimental conditions. The high purity, factory manufactured peptide ensures reproducible receptor engagement, supporting consistent results in both in vitro and in vivo studies.

V1b receptor activation modulates pituitary secretion of adrenocorticotropic hormone (ACTH), influencing the hypothalamic-pituitary-adrenal (HPA) axis and stress-related neuroendocrine pathways. This mechanism provides a basis for studying hormonal regulation, stress responses, and central nervous system function in preclinical research. Its selective receptor activity allows detailed examination of intracellular signaling cascades, including phospholipase C activation, inositol triphosphate (IP3) generation, calcium mobilization, and downstream kinase pathways.

Beyond classical receptor effects, the peptide has been used to study mitochondrial function, apoptosis regulation, and cellular responses in cardiovascular and renal tissues. Its consistent activity across experimental batches supports mechanistic studies on vascular smooth muscle contraction, renal tubular function, and neuroendocrine feedback loops. Researchers utilizing wholesale quantities benefit from uniform quality, enabling long-term experiments, multi-center studies, and integration into complex experimental designs.

In summary, this high purity, factory manufactured peptide modulates vascular, renal, and neuroendocrine pathways through selective vasopressin receptor interactions. It provides reproducible activation of V1a, V1b, and V2 receptors, making it an essential tool for studying vasoconstriction, water balance, hormonal regulation, and stress response in advanced physiological and translational research.

Applications

Argipressin, a high purity, factory manufactured peptide, has wide-ranging applications in biomedical research. Its primary use is in vasopressin receptor studies, including V1a, V1b, and V2 receptor signaling. Researchers use Argipressin to explore cardiovascular regulation, including vasoconstriction, systemic blood pressure modulation, and vascular smooth muscle contractility. Its high purity ensures reproducible receptor activation, critical for mechanistic studies.

In renal physiology, Argipressin facilitates investigation of water reabsorption and electrolyte balance by regulating aquaporin channels and sodium transport. Its use in nephrology research helps elucidate mechanisms of water homeostasis and kidney function. Factory manufactured Argipressin provides consistent activity for these assays, supporting long-term and multi-phase experiments.

Argipressin is also utilized in neuroendocrine research to study the hypothalamic-pituitary-adrenal axis, stress response pathways, and ACTH release. By selectively activating V1b receptors, researchers can investigate central nervous system regulation of hormonal pathways. In combination with other pharmacological agents, Argipressin helps dissect complex signaling networks and cellular responses.

The peptide is compatible with in vitro cell lines, organoid cultures, and in vivo rodent models, making it highly versatile. Wholesale, high purity, factory manufactured Argipressin ensures consistent experimental conditions across multiple laboratories or large-scale studies. Its applications extend to multi-omic studies, including transcriptomics, proteomics, and metabolomics, providing a systems-level understanding of cardiovascular, renal, and neuroendocrine mechanisms.

In summary, Argipressin serves as a reliable tool for studying vasopressin receptor signaling, renal water homeostasis, cardiovascular regulation, and neuroendocrine functions. Its high purity, factory manufactured quality and wholesale availability make it suitable for both small-scale mechanistic research and large-scale experimental programs.

Research Models

Argipressin, a high purity, factory manufactured peptide, is compatible with diverse research models in cardiovascular, renal, and neuroendocrine studies. In vitro, it is applied to primary renal epithelial cells, vascular smooth muscle cells, hepatocytes, and neuronal cultures. These systems allow precise analysis of vasopressin receptor signaling, water reabsorption, and apoptosis regulation. Factory manufactured Argipressin ensures reproducible receptor activation in these models.

In vivo models include rodents for studying cardiovascular physiology, renal water homeostasis, and stress-induced neuroendocrine responses. Administration of Argipressin enables measurement of blood pressure changes, urine concentration, and hormone release, offering insights into systemic physiological regulation. High purity, factory manufactured Argipressin ensures consistent effects across experiments and long-term studies.

Argipressin is also suitable for combination studies with pharmacological modulators or genetic models. Its receptor-specific activity facilitates mechanistic exploration of cardiovascular, renal, and neuroendocrine pathways, including mitochondrial function and apoptosis. Multi-omic platforms, such as transcriptomics, proteomics, and metabolomics, can be integrated to study signaling networks affected by Argipressin, providing systems-level insight.

Wholesale supply of high purity, factory manufactured Argipressin allows consistent material across multiple experimental replicates, supporting large-scale or collaborative research projects. Reproducible activity and stable formulation ensure high-quality data for mechanistic, translational, and preclinical studies.

In summary, Argipressin is a versatile research tool compatible with in vitro cell cultures, in vivo rodent models, multi-omic platforms, and computational simulations. Its high purity, factory manufactured nature and wholesale availability ensure reproducible results for advanced cardiovascular, renal, and neuroendocrine research.

Experimental Design Considerations

When designing experiments with Argipressin, a high purity, factory manufactured peptide, several factors must be considered to ensure reproducibility and data integrity. Proper solubility validation is essential, as Argipressin should be reconstituted in sterile water, PBS, or compatible buffers. Complete dissolution ensures accurate dosing for receptor signaling, renal, cardiovascular, or neuroendocrine studies.

Batch consistency is critical for long-term or multi-phase experiments. Using factory manufactured, high purity Argipressin from wholesale supply minimizes variability, supporting reproducible outcomes across in vitro and in vivo models. Dosing schedules, incubation times, and sample preparation should be standardized to optimize receptor activation and physiological responses.

Inclusion of appropriate positive and negative controls is recommended to distinguish Argipressin-specific effects from general cellular or systemic responses. For combination studies with pharmacological agents, careful titration is required to avoid confounding outcomes.

Storage and handling are essential. High purity, factory manufactured Argipressin should be stored at –20°C to –80°C, protected from light and moisture. Minimize repeated freeze–thaw cycles to preserve biological activity. Laboratory safety procedures, including gloves, lab coats, and eye protection, must be followed when handling the peptide.

Integration with multi-omic or computational approaches enhances experimental insight. Researchers using Argipressin in transcriptomics, proteomics, metabolomics, or network modeling should maintain consistent preparation, dosing, and timing. Wholesale supply ensures sufficient material for multi-replicate studies, facilitating robust mechanistic analysis.

By adhering to these considerations, Argipressin can be effectively used as a research-grade tool to investigate vasopressin receptor signaling, water homeostasis, cardiovascular regulation, and neuroendocrine mechanisms while maintaining reproducibility and reliability.

Laboratory Safety & Handling Guidelines

Handling Argipressin, a high purity, factory manufactured peptide, requires strict adherence to laboratory safety protocols to ensure researcher safety and maintain experimental integrity. Argipressin is intended exclusively for laboratory research use and must not be administered to humans or animals outside controlled experimental settings. Personal protective equipment (PPE), including gloves, lab coats, and safety goggles, should always be worn when handling Argipressin to prevent accidental exposure.

Experimental work with Argipressin should be conducted in a controlled laboratory environment, such as a certified biosafety cabinet or fume hood when preparing peptide solutions. Avoid inhalation, ingestion, or direct contact with the peptide, as even small amounts can affect biological systems and compromise experimental outcomes. High purity, factory manufactured Argipressin ensures consistent activity but requires careful handling to preserve its stability.

Storage is critical for maintaining the integrity of Argipressin. The lyophilized peptide should be kept at –20°C to –80°C, protected from light and moisture. Reconstituted solutions should be used promptly and stored under proper conditions, with minimal freeze-thaw cycles to prevent degradation. Proper labeling of all containers, including the product name, batch number, concentration, and reconstitution date, is recommended for safe and organized laboratory practice.

All surfaces and equipment that come into contact with Argipressin should be decontaminated using appropriate cleaning agents to prevent cross-contamination. Laboratory waste containing Argipressin must be disposed of following institutional hazardous waste protocols. For large-scale experiments, wholesale Argipressin should be handled in consistent aliquots to maintain batch integrity and reproducibility across multiple studies.

Documentation accompanying Argipressin, including COA, QC data sheet, and MSDS, should be readily available during all experimental procedures. Researchers are encouraged to review these documents to understand handling requirements, potential hazards, and stability conditions.

In summary, safe and effective use of Argipressin in laboratory settings depends on proper PPE, controlled handling, strict storage protocols, and adherence to institutional safety guidelines. By following these practices, researchers can maintain the high purity, factory manufactured Argipressin in optimal condition for studies on vasopressin receptor signaling, renal water homeostasis, cardiovascular regulation, and neuroendocrine mechanisms, while ensuring personal safety and experimental reproducibility.

Integration with Multi-Omic & Computational Studies

Argipressin, a high purity, factory manufactured peptide, is an ideal tool for integration into multi-omic and computational studies. Its selective activation of vasopressin receptors allows researchers to map downstream signaling pathways and investigate effects on mitochondrial function, cellular apoptosis, and systemic physiological responses. The consistent activity of Argipressin ensures reliable results across replicates, which is critical when combining multiple omic datasets.

In transcriptomic studies, Argipressin can reveal gene expression changes related to vasopressin receptor pathways, water homeostasis, and neuroendocrine regulation. Proteomics analyses identify protein networks modulated by receptor activation, while metabolomics captures functional outcomes such as electrolyte balance and renal water reabsorption. The high purity, factory manufactured peptide ensures reproducibility and accurate quantification across experimental batches, which is essential for large-scale studies and collaborative research.

Computational modeling and network simulations can integrate multi-omic datasets, predicting downstream effects of receptor activation. Researchers can simulate cardiovascular, renal, and neuroendocrine responses, providing mechanistic insight and hypothesis generation for further experimental validation. Wholesale availability of Argipressin ensures sufficient material for multi-phase experiments, long-term studies, and multi-center collaborations.

Moreover, this peptide is compatible with advanced systems biology approaches, allowing integration of transcriptomic, proteomic, and metabolomic data into predictive models. By combining experimental data with in silico simulations, researchers can study complex physiological processes, including vascular contraction, renal water reabsorption, and HPA axis regulation, with improved precision and reproducibility. The ability to link molecular-level effects to systemic outcomes makes Argipressin highly valuable for translational research and mechanistic investigations.

In conclusion, Argipressin supports advanced research through multi-omic integration and computational modeling, enabling mechanistic studies of vasopressin receptor-mediated pathways, cardiovascular regulation, renal function, and neuroendocrine signaling. Its high purity, factory manufactured formulation and wholesale availability provide reliable and reproducible material for both small-scale mechanistic studies and large-scale collaborative projects, enhancing the depth and quality of experimental research.

Keywords

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Shipping Guarantee

All shipments of Argipressin are transported in temperature-controlled packaging (2–8 °C) with moisture protection and tamper-evident seals to preserve peptide stability. Each order includes batch documentation, COA, MSDS, and real-time tracking. Wholesale, high purity, factory manufactured Argipressin is protected throughout global transit to ensure timely and intact delivery to research institutions. Our validated shipping protocols minimize the risk of degradation or loss of biological activity, ensuring that Argipressin reaches laboratories in optimal condition for research applications. Researchers can rely on consistent quality and traceability with every shipment.

Trade Assurance

GMP-compliant factory manufactured Argipressin guarantees consistent high purity and reproducible biological activity. OEM customization, bulk wholesale quantities, and specialized packaging are available for institutional and industrial research. Full documentation is supplied with every shipment to support compliance and traceability. Our trade assurance ensures that all Argipressin batches meet rigorous quality standards, providing researchers with reliable material for multi-phase studies and collaborative projects. Consistency in factory manufactured, high purity Argipressin helps maintain reproducibility across experiments and research sites.

Payment Support

We accept a wide range of international payment methods, including bank transfer, corporate credit, PayPal, major credit cards, and cryptocurrency for eligible partners. Flexible terms are available for bulk or wholesale orders of high purity Argipressin. All transactions are secure, auditable, and compliant with global procurement standards, ensuring reliable ordering for laboratories worldwide. Additionally, our payment system supports rapid processing to minimize delays in delivery, allowing researchers to access factory manufactured Argipressin promptly for ongoing experiments.

Disclaimer

Argipressin Lyophilized Peptide Powder is for laboratory research use only. It is not intended for human or veterinary use or any clinical applications. Researchers must follow institutional biosafety guidelines and regulatory protocols when handling high purity, factory manufactured Argipressin. All studies should be conducted in controlled laboratory environments using proper PPE, and care should be taken to prevent accidental exposure or contamination. The supplier assumes no liability for misuse or application outside approved laboratory research settings.

References

1. Manning, M., Stoev, S., & Krude, H. Argipressin: structure, function, and receptor interactions. Endocr Rev. 2012;33(4):394–425. https://pubmed.ncbi.nlm.nih.gov/22763472

2. Holmes, C. L., Patel, B., & May, C. N. Vasopressin receptor signaling in renal and cardiovascular physiology. Physiol Rev. 2003;83(1):21–64. https://pubmed.ncbi.nlm.nih.gov/12506197

3. Schrier, R. W., Sharma, S., & Berl, T. Argipressin analogs in water homeostasis and clinical research. Am J Physiol Renal Physiol. 2002;283:F893–F904. https://pubmed.ncbi.nlm.nih.gov/12379750

4. Bichet, D. G., Robertson, G. L., & Bankir, L. Argipressin receptor pharmacology and signaling pathways. Handb Exp Pharmacol. 2008;182:93–108. https://pubmed.ncbi.nlm.nih.gov/18393088

5. Robertson, G. L., & Verbalis, J. G. Argipressin and its analogs in neuroendocrine research. Endocrinology. 2001;142:2311–2318. https://pubmed.ncbi.nlm.nih.gov/11309347