Azathioprine Tablets 50mg – For Research Use Only
$2.00
Azathioprine Tablets contain 50mg of azathioprine per tablet, 25 tablets per box. Manufactured by Zhejiang Autocare Pharmaceutical Group under license H33020153. Widely used in research modeling immunosuppression, autoimmune disease mechanisms, and organ rejection pathways. Supports wholesale & retail orders.?For wholesale prices, other specifications and uses, please consult our staff?
描述
Azathioprine is a purine analog and immunosuppressive antimetabolite that suppresses lymphocyte proliferation by inhibiting purine synthesis and incorporation of 6-thioguanine nucleotides into DNA and RNA. It is metabolized into 6?mercaptopurine and its active thioguanine nucleotides, reducing both cellular and humoral immune responses. In research, Azathioprine is often applied in models of autoimmune disease, organ transplantation, inflammatory bowel disease, myasthenia gravis, and JAK/STAT or NF??B pathway modulation. Provided as 50?mg scored tablets, 25 per box. For laboratory research use only.
Product Specifications
| Parameter | Detail |
|---|---|
| Product Name | Azathioprine Tablets |
| Synonyms | Azathioprine; Imuran; 6-MP prodrug; Purine antimetabolite |
| Strength & Packaging | 50?mg per tablet, 25 tablets per box |
| Dosage Form | Oral scored tablet |
| Manufacturer | Zhejiang Autocare Pharmaceutical Group Co., Ltd. |
| Approval Number | H33020153 |
| Drug Standard Code | 86904608000274 |
| Barcode | 6916370000035 |
| CAS Number | 446?86?6 (azathioprine sodium) |
| Molecular Formula | C?H?N?O?S |
| Molecular Weight | ~277.26?Da |
Mechanism of Action & Research Applications
Azathioprine metabolizes into 6-mercaptopurine and thioguanine nucleotides which inhibit purine synthesis, suppress lymphocyte proliferation, and induce T-cell apoptosis via Rac1 signaling and NF??B pathway modulation. It is widely used in experimental immunology to model autoimmune disease, transplant rejection, inflammatory bowel disease, and cytokine-driven signaling research (e.g., JAK/STAT)
Side Effects (For Reference Only in Research Models)
Clinical analogs report myelosuppression (especially in TPMT or NUDT15-deficient models), increased infection risk, hepatotoxicity, gastrointestinal upset, headache, fever, rare malignancy risk, and risk of lymphoma – critical for defining safety thresholds in experimental protocols.
Disclaimer
Azathioprine Tablets are strictly intended for laboratory research use only. Not for clinical, veterinary, or diagnostic use.
其他信息
| 重量 | 0.6 公斤 |
|---|---|
| 尺寸 | 23 × 38 × 23 厘米 |
相关产品
-
Adenosylcobalamin Capsules 0.5mg (Cobamamide Capsules) – AR Grade Factory low price wholesale
High-purity Adenosylcobalamin (Cobamamide) Capsules, ideal for treating vitamin B12 deficiency and supporting cellular energy metabolism. Available for wholesale and retail.?For wholesale prices, other specifications and uses, please consult our staff? $3.00 -
Hydroxychloroquine Sulfate Tablets 0.2g × 24 Tablets – AR Grade
Hydroxychloroquine Sulfate Tablets (Ai?Shen) offer reliable pharmaceutical-grade quality at 0.2g per tablet, packaged in 24-tablet boxes. Manufactured by Suzhou Changzheng-Xinkai Pharmaceutical Co., Ltd., this product is approved under H20243758 and ideal for research applications. Wholesale and retail supported.?For wholesale prices, other specifications and uses, please consult our staff? $1.00 -
Mycophenolate Mofetil Tablets 0.5g – For Laboratory Research Only
Mycophenolate Mofetil Tablets deliver 0.5g of active compound per tablet and are primarily used in immunosuppressive research. Each bottle contains 100 tablets. For research use only—not for human or veterinary application.?For wholesale prices, other specifications and uses, please consult our staff? $2.00 -
Amimestrocel Injection 12ml – For laboratory only
Amimestrocel Injection is a cell-based injectable product containing 6×10^7 cells per 12ml vial. Manufactured by Platinum Excellence Biotech (Beijing) Co., Ltd., it is approved by the China NMPA for experimental research purposes only. Suitable for wholesale and retail in laboratory research settings.?For wholesale prices, other specifications and uses, please consult our staff? $3.00
评价
目前还没有评价