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Bombesin (CAS 31362-50-2) – High Purity Peptide for Research
$2.00
Bombesin is a biologically active neuropeptide with 99.92% purity. It plays critical roles in gastrointestinal regulation and cancer research. Produced under GMP standards, it is ideal for laboratory and research use.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Bombesin (CAS 31362-50-2) is a highly purified peptide derived from amphibians that mimics mammalian gastrin-releasing peptide (GRP). It is widely studied for its role in stimulating the release of gastrointestinal hormones and regulating smooth muscle contraction. Bombesin binds to specific G-protein coupled receptors, influencing various physiological processes including satiety, thermoregulation, and cellular proliferation.
In cancer research, Bombesin is particularly valuable due to its overexpression in several tumor types, including prostate and lung cancers, making it a useful target for diagnostic and therapeutic studies. Its neuropeptide activity also extends to neurological pathways, offering a broad scope for experimental investigations.
Manufactured in a GMP-certified facility, Bombesin with 99.92% purity is supplied for experimental and research applications only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Bombesin |
| CAS Number | 31362-50-2 |
| Purity | 99.92% |
| Appearance | White to off-white powder |
| Molecular Formula | C65H103N17O14S |
| Molecular Weight | ~1619.8 Da |
| Storage | -20°C, dry and dark place |
| Manufacturing Standard | GMP Certified Factory |
Mechanism of Action & Research Applications
Bombesin acts as an agonist of the gastrin-releasing peptide receptor (GRPR), a G-protein coupled receptor widely expressed in gastrointestinal tissues and certain cancers. By binding to GRPR, Bombesin triggers intracellular signaling cascades that regulate hormone secretion, smooth muscle activity, and cellular proliferation.
Its role in stimulating gastrin release and modulating digestive functions makes it valuable in gastroenterology research. Additionally, Bombesin’s expression in various tumors has made it a focus in oncology research for understanding tumor growth and as a potential therapeutic target. Neurophysiological studies also leverage Bombesin to explore neuromodulatory functions.
Side Effects (For Reference Only in Models)
Since Bombesin is used exclusively for research purposes, detailed clinical side effects are not established. However, it may induce physiological changes in experimental models such as increased hormone secretion and modulation of gastrointestinal motility.
Disclaimer
Bombesin (CAS 31362-50-2) is intended strictly for laboratory research use only. Not for human or animal therapeutic use. All information provided is for experimental purposes and does not constitute medical advice.
Additional information
| Weight | 0.9 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
1 review for Bombesin (CAS 31362-50-2) – High Purity Peptide for Research
What is Bombesin?
Bombesin is a neuropeptide that mimics mammalian gastrin-releasing peptide and is used in research to study gastrointestinal function and cancer.
What is the mechanism of action of Bombesin?
Bombesin binds to gastrin-releasing peptide receptors (GRPR), activating cellular signaling that regulates hormone secretion and cell proliferation.
What research applications does Bombesin have?
Bombesin is used in studies of gastrointestinal physiology, cancer biology (especially prostate and lung cancer), and neuromodulation research.
Is Bombesin a hormone or a neurotransmitter?
Bombesin functions primarily as a neuropeptide and hormone analogue involved in digestive and neurological signaling pathways.
What triggers the release of Bombesin?
In natural systems, Bombesin-like peptides are released in response to food intake and other physiological stimuli affecting the gastrointestinal tract.
Can Bombesin be used in clinical treatments?
Bombesin is strictly for experimental and research use and is not approved for therapeutic or clinical applications.
How should Bombesin be stored?
Store Bombesin at -20°C in a dry, dark environment to maintain stability and activity.
Is Bombesin manufactured in GMP conditions?
Yes, this Bombesin is produced in a GMP-certified factory to ensure high quality and purity for research use.
What purity level does Bombesin have?
This product has a purity of 99.92%, suitable for sensitive experimental procedures.
Is Bombesin safe for animal studies?
Bombesin is intended for laboratory research including animal models but should be handled with care according to safety protocols.
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Well packaged and delivered promptly. Overall a reliable purchase.