描述
Bremelanotide acetate is a synthetic cyclic heptapeptide analog of ??melanocyte stimulating hormone (??MSH), functioning as a non-selective agonist of melanocortin receptors, especially MC1R and MC4R. MC4R activation is linked with CNS pathways regulating sexual desire and arousal. While its therapeutic mechanism remains not fully defined, it is FDA-approved for addressing hypoactive sexual desire disorder (HSDD) in premenopausal women.
This GMP-produced peptide (?99.98% purity) is optimized for preclinical studies on CNS function, sexual motivation, melanocortin signaling, and related neuroendocrine pathways.
For laboratory research use only. Not for human or clinical use.
Product Specifications
Parameter | Details |
---|---|
Product Name | Bremelanotide Acetate (PT-141 acetate) |
CAS Number | 1607799?13?2 |
Purity | ?99.98% (HPLC) |
Molecular Formula | C??H??N??O?? |
Molecular Weight | ~1085.23 Da |
Mechanism | Non-selective MCR agonist (MC1R, MC4R dominant) |
Appearance | White to off-white lyophilized powder |
Solubility | Soluble in DMSO (?33 mg/mL); use PBS/water for assays |
Storage | –20?°C, protected from light and moisture |
Manufacturing | GMP-compliant facility |
Intended Use | For laboratory research use only |
Mechanism of Action & Research Applications
Bremelanotide acetate targets melanocortin receptors, non-selectively activating MC1R and MC4R—key to melanocyte pigmentation and sexual behavior, respectively. Research applications include:
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Central nervous system studies on sexual desire and arousal
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Melanocortin signaling pathway investigations
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Behavioral pharmacology and neurotransmitter modulation
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Sexual dysfunction and neuroendocrine research
Side Effects (Research Context Only)
In experimental settings, activation of melanocortin receptors may result in:
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Transient blood pressure changes and heart rate fluctuation
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Nausea, injection site reactions, and pigmentation changes
These outcomes have been mainly observed in clinical scenarios and are referenced here for research context only.
Disclaimer
This compound is strictly for laboratory research use only. It is not approved for human, clinical, or veterinary use. Use in compliance with institutional safety protocols only.
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