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Bumetanide Injection 0.5mg/2ml (Research Grade) – For Laboratory Use Only
$1.00
Bumetanide Injection (0.5mg/2ml), supplied in boxes of 5 vials. Manufactured by Henan Xintai Pharmaceutical Co., Ltd. For laboratory research only. Wholesale & retail available.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Bumetanide is a potent loop diuretic that inhibits the Na?/K?/2Cl? symporter in the thick ascending limb of the loop of Henle. It is used in research involving fluid and electrolyte balance, kidney function, hypertension, and heart failure models.
This injectable formulation contains 0.5mg of Bumetanide per 2ml vial, with 5 vials per box. It is widely employed in pharmacodynamic and pharmacokinetic studies of diuretics and renal function modulators.
Approved by the China NMPA (H20057376) and manufactured by Henan Xintai Pharmaceutical Co., Ltd.
For laboratory research use only. Not for clinical or human use.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Bumetanide Injection |
| Generic Name | Bumetanide |
| CAS Number | 28395-03-1 |
| Molecular Formula | C17H20N2O5S |
| Molecular Weight | 364.42 g/mol |
| Dosage Form | Injection |
| Strength | 0.5mg/2ml |
| Quantity | 5 vials per box |
| Approval Number | H20057376 (China NMPA) |
| Product Code | 86903091000334 |
| Manufacturer | Henan Xintai Pharmaceutical Co., Ltd. |
| Barcode | 6974351310061 |
| Intended Use | For laboratory research use only |
| Storage Conditions | Store below 25°C, away from light and moisture |
Mechanism of Action & Research Applications
Bumetanide selectively inhibits the Na?-K?-2Cl? cotransporter (NKCC2) in the loop of Henle, leading to significant diuresis and natriuresis. In laboratory settings, it is often used to model fluid retention disorders, renal dysfunction, loop diuretic response, and electrolyte imbalances.
It is also studied in neurodevelopmental and epilepsy research due to its influence on chloride transport in neurons.
Safety & Handling
Use Restriction: For research use only. Not for human or animal use.
Protective Equipment: Wear gloves, lab coat, and eye protection when handling.
Storage: Store in original packaging, sealed, below 25°C.
Disposal: Follow chemical waste disposal regulations.
Research Use Disclaimer
This product is intended exclusively for laboratory research. It is not approved for use in humans or animals. Misuse may pose health or legal risks. Use only in certified research facilities under proper supervision.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
Q1: Is this product intended for human use?
A1: No. This product is strictly for laboratory research use only.
Q2: Can I purchase Bumetanide Injection in bulk?
A2: Yes. We support both wholesale and retail orders. Contact us for bulk pricing.
Q3: Is a Certificate of Analysis (COA) available?
A3: Yes, COA and SDS documents are available upon request.
Q4: What research applications is Bumetanide used for?
A4: Common studies include renal pharmacology, diuretic response, electrolyte regulation, and central nervous system modulation.
Q5: What’s the packaging format?
A5: Each box contains 5 vials, with 0.5mg of Bumetanide in 2ml per vial.
Q6: Is Bumetanide related to Furosemide?
A6: Yes. Both are loop diuretics, but Bumetanide is more potent and shorter-acting, often preferred in certain lab studies.
Q7: Can Bumetanide be used in seizure or autism research?
A7: Yes, it is studied for its effect on neuronal chloride transport, particularly in autism spectrum disorder and neurodevelopmental research.
Q8: What’s the CAS number of Bumetanide?
A8: The CAS number is 28395-03-1, commonly used for ordering and regulatory purposes.
Q9: Is this product compatible with rodent models?
A9: Yes, it's widely used in rat and mouse models for renal and neuropharmacological studies.
Q10: Are there known side effects in lab animals?
A10: Common lab-observed effects include electrolyte imbalances, dehydration, and transient hypotension.
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