Description

BW-180C (DADLE) is a synthetic enkephalin analog peptide that selectively activates ?-opioid receptors, with additional activity at ?-opioid receptors. In vivo, it demonstrates potent antinociceptive effects and protective effects against ischemia-reperfusion injury, particularly in liver models. In vitro, it can reversibly suppress neuronal transcription in SH-SY5Y cells without cytotoxicity. Produced under GMP standards with purity of ?99.92%, BW-180C is ideal for neuroscience, GPCR, and cellular protection studies. For laboratory research use only.

Product Specifications

Mechanism of Action & Research Applications

BW-180C acts as a ?-opioid receptor agonist (also engaging ?-opioid receptors) to produce analgesic effects. Experimental studies show it can protect liver tissue during ischemia-reperfusion injury and modulate neuronal transcription without causing cell death. These properties make it valuable in research on pain pathways, opioid receptor pharmacology, neuroprotection, and ischemic injury mitigation. For laboratory research use only.

Side Effects (For Reference Only in Models)

In vitro, BW-180C may reversibly suppress transcription in neural cells (e.g., SH-SY5Y) without inducing cell injury. In vivo, high doses might influence pain perception and stress response pathways. Observed effects are for experimental context only. For laboratory research use only.

Disclaimer

BW-180C is supplied strictly for laboratory research use only. It is not intended for human or veterinary use. Handle following institutional safety and regulatory protocols.