Celecoxib Capsules 1.2g – Grade COX?2 Inhibitor
$1.00
Celecoxib is a selective COX?2 inhibitor (NSAID) commonly used in preclinical research to study inflammation, pain, cancer prevention, and cardiovascular risk. Each capsule contains 200?mg celecoxib. ?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Celecoxib Capsules |
| Generic Name | Celecoxib |
| CAS Number | 169590?42?5 |
| Molecular Formula | C??H??F?N?O?S |
| Molecular Weight | ~381.37?g/mol |
| Dosage Form | Oral capsule |
| Strength | 200?mg per capsule |
| Pack Size | (e.g., 30 capsules) |
| Manufacturing Approval | N/A (research grade) |
| Manufacturer | Sichuan Xinston Pharmaceutical |
| Storage | Store at 15–25?°C, protect from moisture and light |
| Intended Use | Laboratory research use only |
Mechanism of Action
Celecoxib selectively inhibits cyclooxygenase?2 (COX?2), reducing prostaglandin synthesis involved in inflammation, pain, and fever—while sparing COX?1, reducing gastrointestinal side effects in research models.
zh.wikipedia.orgaccessdata.fda.gov+2de.wikipedia.org+2zh.wikipedia.org+2dailymed.nlm.nih.govncbi.nlm.nih.gov+1medcentral.com+1
Research Applications & Pharmacology
-
Inflammation & pain models: Used in osteoarthritis, rheumatoid arthritis, nociceptive pain, and dysmenorrhea studies.
-
Cancer/prevention models: Investigated for chemoprevention in familial adenomatous polyposis and COX?2?dependent tumor biology (e.g., colorectal, neuroblastoma).
-
Cardiovascular risk profiling: Employed in studies assessing thrombotic risk and COX?2 inhibitor safety.
-
Pharmacokinetics: Well absorbed, peak plasma 2–4 hrs, half-life ~6–12 hrs, highly protein?bound (~97%), metabolized by CYP2C9/CYP3A4 to inactive metabolites excreted in urine/feces.
Safety Profile & Handling
Common adverse effects (clinical/preclinical context):
-
GI: bleeding, ulceration, perforation
-
Cardiovascular: increased risk of MI and stroke
-
Others: headache, dizziness, hypertension, renal and hepatic effects
Lab handling recommendations:
-
Use personal protective equipment and follow standard handling for NSAIDs.
-
Monitor study models for GI, cardiovascular, renal, and hepatic markers.
-
Use lowest effective dose for shortest duration.
-
Dispose of unused material as chemical waste.
?? Research?Use Disclaimer
This product is intended solely for laboratory research, and is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may pose safety risks and compromise data integrity.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 16 × 18 × 16 厘米 |
相关产品
-
Sugammadex Sodium 200?mg/2?mL ×?10 Vials Wholesale price comparison
Sugammadex sodium is a selective relaxant binding agent (SRBA) designed for rapid and safe reversal of neuromuscular blockade induced by steroidal muscle relaxants such as rocuronium and vecuronium. Each 2?mL vial contains 200?mg of sugammadex sodium. Manufactured by Guangdong Jiabo Pharmaceutical Co., Ltd., approval under NMPA H20223277, product code 86904948001252, barcode 6942746533371.
?? For laboratory research use only.?Please consult the staff for other purposes? $2.00 -
Propofol 20?mg/mL MCT/LCT Emulsion Injection 20?mL ×?5 Vials
This propofol formulation uses a medium-chain and long-chain triglyceride (MCT/LCT) emulsion, designed to produce equivalent anesthetic effects compared to long-chain-only emulsions while reducing injection pain and minimizing triglyceride accumulation. Each 20?mL vial contains 400?mg propofol (20?mg/mL).
?? For laboratory research use only?Please consult staff for other specifications and uses? $1.00 -
Lornoxicam 8?mg ×?6 Ampoules Wholesale price comparison
Lornoxicam is a potent oxicam?class NSAID with rapid onset and short half-life, used in preclinical pain and inflammation research. Each ampoule contains 8?mg for IV/IM use. Manufactured by Harbin Sanlian Pharmaceutical Co., Ltd., approval under NMPA H20057160, product code 86903662001906.
?? For laboratory research use only.?Please consult the staff for other purposes? $8.60 -
Bupivacaine Hydrochloride 37.5?mg ×?5 Vials Wholesale price comparison
Bupivacaine hydrochloride is a long-acting amide-type local anesthetic widely used in preclinical studies for nerve block, infiltration, epidural, and spinal anesthesia. Each box contains five 5?mL vials (37.5?mg per vial). Manufactured by Hunan Zhengqing Pharmaceutical Group Co., Ltd., approved under NMPA H43021018, product code 86904152004254.
?? For laboratory research use only.?Please consult the staff for other purposes? $2.00
评价
目前还没有评价