Description
Cimetidine Tablets Product Specifications
| Specification | Description |
|---|---|
| Product Name | Cimetidine Tablets (Jiajian) |
| Generic Name | Cimetidine |
| CAS Number | 51481?61?9 |
| Formulation | Oral tablet |
| Strength | 0.2?g (200?mg) per tablet |
| Pack Size | 100 tablets per bottle |
| Approval Number | H41023429 (NMPA, China) |
| Product Code | 86903227000313 |
| Manufacturer | Henan Zhongjie Pharmaceutical Co., Ltd. |
| Barcode | – (not provided) |
| Storage Conditions | Store below 30?°C in a cool, dry place |
| Intended Use | For laboratory research only |
Cimetidine Tablets Mechanism of Action
Cimetidine is a competitive histamine H? receptor antagonist that inhibits gastric acid secretion by blocking H? receptors on gastric parietal cells. This action reduces basal and nocturnal acid production go.drugbank.com+1en.wikipedia.org+1. It also weakly inhibits CYP450 enzymes, which is valuable in drug interaction research .
Research Applications & Pharmacology
Acid suppression studies: ideal for research into GERD, peptic ulcer, and hypersecretory models
Pharmacokinetics and drug interaction: useful for CYP450 metabolism studies, especially CYP1A2, CYP2D6, and CYP3A4
Anti-inflammatory and repurposing research: emerging potential in oncology and immune modulation
Preclinical dose-response assessments: recommended in vitro concentrations range from 10–100?µM; in vivo studies often use 50–200?mg/kg protocols.
Safety Profile & Handling
Preclinical Safety: Generally low toxicity, adverse effects may include minor pH shifts or enzyme interactions
Handling precautions: Use lab PPE—lab coat, gloves, eye protection; avoid inhaling tablet dust
Storage: Keep in a cool, dry area, protected from light and heat
Waste Disposal: Follow institutional hazardous waste guidelines
Core Keywords
Cimetidine, H? receptor antagonist, cimetidine tablets, CAS 51481?61?9, gastric acid suppression, lab research chemical, wholesale cimetidine, drug interaction study
Research-Use Disclaimer
This product is intended exclusively for laboratory research use and is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Improper handling or unauthorized use may pose health risks. Always follow your institution’s guidelines.


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