Copper Tripeptide | CAS 89030-95-5 | Regenerative Peptide Complex for Skin Repair and Anti-Aging Research | Factory Supply

Description

Product Description

Copper Tripeptide, commonly known as GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Cu²⁺), is a small, naturally occurring peptide complex that plays a crucial role in skin homeostasis and regeneration. Initially identified for its capacity to bind copper ions, GHK-Cu has gained widespread attention in cosmetic and dermatological research for its multifunctional biological activities, particularly in skin regeneration, collagen synthesis, and antioxidant protection.

In tissue repair and wound healing studies, Copper Tripeptide acts as a potent chemoattractant for inflammatory cells, endothelial cells, and fibroblasts. Upon proteolytic cleavage from extracellular matrix proteins, GHK-Cu becomes bioavailable, initiating a cascade of molecular events that modulate gene expression, protein synthesis, and cellular signaling pathways.

One of the most prominent mechanisms of GHK-Cu is its ability to enhance extracellular matrix (ECM) protein synthesis. Research demonstrates that it stimulates mRNA expression and subsequent production of collagen types I and III, elastin, glycosaminoglycans, and proteoglycans in dermal fibroblasts. This activity directly contributes to improved skin elasticity, structural integrity, and the restoration of dermal architecture, making it a key molecule for anti-aging and skin rejuvenation studies.

Copper Tripeptide also exerts a potent antioxidant effect. By stabilizing reactive oxygen species and chelating free copper ions, GHK-Cu reduces oxidative stress, prevents lipid peroxidation, and protects cellular components from oxidative damage. These antioxidant properties are especially valuable in cosmetic peptide research, where oxidative stress is a major driver of skin aging, photoaging, and loss of dermal resilience.

Additionally, GHK-Cu modulates inflammatory pathways. It suppresses pro-inflammatory cytokines, recruits immune cells to injury sites, and promotes tissue remodeling. In vitro studies reveal that GHK-Cu enhances fibroblast proliferation, endothelial cell migration, and angiogenesis, facilitating the regeneration of damaged dermal tissue. This combination of anti-inflammatory, antioxidant, and regenerative effects positions Copper Tripeptide as a highly versatile peptide in both cosmetic and clinical research models.

Copper Tripeptide also influences cellular signaling pathways involved in tissue repair. It regulates metalloproteinases (MMPs), growth factors, and transcription factors that govern dermal matrix turnover and tissue remodeling. By maintaining a balance between ECM degradation and synthesis, GHK-Cu ensures healthy skin structure and counteracts wrinkle formation, dermal thinning, and loss of firmness associated with aging.

In cosmetic formulation studies, Copper Tripeptide is appreciated for its bioavailability and skin penetration, making it suitable for topical delivery. Researchers use GHK-Cu to investigate synergistic effects with other cosmetic peptides, antioxidants, and hydrating molecules, aiming to maximize anti-aging outcomes, improve skin elasticity, and reduce the appearance of fine lines.

Overall, Copper Tripeptide serves as a gold standard peptide model for studies on skin regeneration, wound healing, collagen synthesis, and antioxidant defense. Its dual role in molecular signaling and ECM modulation provides researchers with a comprehensive tool to explore anti-aging interventions, cellular repair mechanisms, and cosmetic peptide efficacy.

Product Specifications

Mechanism of Action

Copper Tripeptide (GHK-Cu) functions through three primary mechanisms:

1. Collagen and ECM Stimulation:
   GHK-Cu upregulates gene expression for collagen types I and III, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. This leads to enhanced extracellular matrix formation, improved skin elasticity, and dermal structural integrity.

2. Antioxidant Protection:
   By chelating copper ions and scavenging reactive oxygen species, GHK-Cu prevents oxidative damage to proteins, lipids, and nucleic acids. This antioxidant effect reduces photoaging and maintains cellular homeostasis.

3. Tissue Repair and Regeneration:
   GHK-Cu serves as a chemoattractant for fibroblasts, endothelial cells, and inflammatory cells during wound healing. It promotes angiogenesis, cell proliferation, and tissue remodeling, facilitating the repair of damaged dermal tissue.

Additional molecular effects include modulation of metalloproteinases (MMPs), growth factors, and transcription factors involved in ECM turnover, allowing controlled tissue remodeling and anti-aging benefits.

Side Effects

Copper Tripeptide is generally considered safe in laboratory research. It is a naturally occurring peptide with minimal cytotoxicity. Potential side effects are typically limited to over-concentrated solutions in in vitro assays, which may affect experimental parameters.

This compound is not intended for human or cosmetic use. Proper laboratory handling, protective equipment, and adherence to biosafety protocols are required. Its use should be restricted to in vitro, ex vivo, or controlled experimental studies.

Keywords

Copper Tripeptide, GHK-Cu, CAS 89030-95-5, collagen synthesis, skin regeneration, wound healing, antioxidant peptides, cosmetic peptides, anti-aging peptide research, dermal repair

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

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Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.