Dapoxetine Hydrochloride Tablets – Bongo® / Hongqi 30?mg ×?8
$1.00
Dapoxetine is the first fast-acting selective serotonin reuptake inhibitor (SSRI) developed specifically for premature ejaculation (PE). This product offers 30?mg film-coated tablets supplied as 4 tablets per blister, 2 blisters per box. Intended exclusively for laboratory and preclinical research, not approved for clinical, therapeutic, or veterinary use.
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Dapoxetine Hydrochloride Tablets (Bongo® / Hongqi Pharmaceutical) |
| Generic Name | Dapoxetine Hydrochloride (C??H??NO·HCl) |
| CAS Number | 119356?77?3 (wikipedia.org) |
| Molecular Formula | C??H??NO·HCl ©C??H??NO·HCl |
| Molecular Weight | ~305.4?g/mol |
| Dosage Form | Film?coated oral tablet |
| Strength | 30?mg per tablet |
| Pack Size | 4 tablets × 2 blisters |
| Approval No. | China NMPA H20213748 |
| Product Code | 86910323000123 |
| Manufacturer | Shenyang Hongqi Pharmaceutical Co., Ltd. |
| Barcode | 6975167815429 |
| Storage Conditions | Store at 15–25?°C; protect from moisture and light |
| Intended Use | Laboratory research only |
Mechanism of Action
Dapoxetine is a short-acting SSRI that inhibits serotonin reuptake in the central nervous system, enhancing serotonin activity at the synapse. This action prolongs ejaculatory latency through modulation of sensory-spinal-brain circuits (e.g., 5?HT?A, 5?HT?B, 5?HT?C receptors).
Research Applications & Pharmacology
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Premature Ejaculation (PE) Models: Significantly increases intravaginal ejaculatory latency time (IELT) when administered on-demand (30?mg, sometimes 60?mg) .
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Mechanistic CNS Studies: Helps explore serotonin signaling and ejaculatory control pathways .
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Pharmacokinetics: Rapid absorption (T??? ??1?h), short initial half-life (1–2?h), terminal half-life (~15–19?h), mainly metabolized via CYP2D6 and CYP3A4, highly protein-bound (>99%) .
Safety Profile & Handling
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Common Adverse Events: Nausea, headache, dizziness, diarrhea, insomnia .
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Serious Risks: Rare syncope observed shortly after dosing; caution advised in cardiovascular research tga.gov.au.
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Handling: Store properly, use PPE, and discard expired products per lab protocol.
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Contraindications: Avoid in hepatic impairment models or when co-administered with strong CYP3A4 inhibitors or serotonergic drugs
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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