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Desvenlafaxine Succinate SR Tablets 50mg
$1.00
Desvenlafaxine Succinate Sustained-release Tablets (50mg) are extended-release formulations of a serotonin-norepinephrine reuptake inhibitor (SNRI), useful in experimental studies related to depression, mood regulation, and neurochemical imbalance. Manufactured by CSPC Ouyi Pharmaceutical Co., Ltd. and approved under Chinese NMPA H20233840. Intended strictly for scientific research use.?? For laboratory research only.?Please consult staff for other specifications and uses?
Description
Desvenlafaxine is the active metabolite of venlafaxine and functions as an SNRI. It is often utilized in preclinical CNS studies examining neurotransmitter uptake inhibition, mood disorders, and neuroplasticity. This sustained-release formulation ensures prolonged plasma concentration for extended pharmacodynamic observation.
Desvenlafaxine Succinate Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Desvenlafaxine Succinate Sustained-release Tablets |
| Synonyms | Desvenlafaxine ER, DVS, O-desmethylvenlafaxine |
| CAS Number | 93413-62-8 |
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.38 g/mol |
| Strength | 50mg per tablet |
| Formulation | Sustained-release tablet |
| Pack Size | 14 tablets per box |
| Dosage Form | Oral tablet |
| Approval Number | H20233840 (NMPA, China) |
| Drug Code | 86902770004779 |
| Manufacturer | CSPC Ouyi Pharmaceutical Co., Ltd. |
| Storage Conditions | Store below 25°C, away from moisture |
| Intended Use | Laboratory research only |
Desvenlafaxine Succinate Mechanism of Action
Desvenlafaxine acts by selectively inhibiting the reuptake of serotonin and norepinephrine in the CNS. It increases the synaptic concentration of these neurotransmitters, helping stabilize mood in experimental models. Its sustained-release formulation ensures consistent drug levels in long-duration studies.
Research Applications
Mood Disorder Models
Supports the evaluation of SNRI efficacy in depressive and anxiety-like behaviors in rodents or in vitro systems.Neurotransmitter Studies
Useful in serotonin-norepinephrine transport and receptor pathway mapping.Chronic Stress Research
Employed in chronic mild stress and neuroendocrine axis studies to simulate human depressive pathology.Drug-Drug Interaction Studies
Used in CYP metabolism and transporter interaction profiling.
Safety & Handling
Handling: Use standard protective equipment in research environments.
Storage: Keep sealed and dry at room temperature (?25°C).
Shelf Life: Stable up to 24–36 months when properly stored.
Disclaimer: Not suitable for human or veterinary use.
Research Use Only Disclaimer
This product is designated solely for laboratory research. It is not intended for therapeutic, diagnostic, clinical, or human consumption. Handle according to institutional biosafety guidelines.
Additional information
| Weight | 1.2 kg |
|---|---|
| Dimensions | 62 × 23 × 62 cm |
Q1: What is the difference between venlafaxine and desvenlafaxine?
A1: Desvenlafaxine is the active metabolite of venlafaxine and has more predictable pharmacokinetics.
Q2: What makes this sustained-release (SR)?
A2: It’s designed for extended release to maintain therapeutic levels over a longer period for prolonged CNS effect observation.
Q3: Can this be used in behavioral animal models?
A3: Yes, it’s frequently used in depressive and anxiety disorder models in rodents for CNS research.
Q4: Can I request COA/SDS?
A4: Yes, Certificates of Analysis and Safety Data Sheets are available upon request.
Q5: Do you support large wholesale orders?
A5: Absolutely. We support both small lab quantities and bulk institutional procurement.
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