Description
Product Specifications
| Parameter | Description |
|---|---|
| Product Name | Dexlansoprazole Injection |
| Generic Name | Dexlansoprazole (R?enantiomer of Lansoprazole) |
| CAS Number | 138530?94?6 en.wikipedia.org+2medcentral.com+2pmc.ncbi.nlm.nih.gov+2 |
| Molecular Formula | C??H??F?N?O?S |
| Molecular Weight | 369.36?g/mol |
| Formulation | Freeze?dried sterile powder for injection; reconstitute before use |
| Strength | 15?mg per vial |
| Pack Size | 10 vials per box |
| Approval Number | H20240001 (NMPA, China) |
| Manufacturer | Jiangsu AosaiKang Pharmaceutical Co., Ltd. |
| Storage Conditions | Store at 2–8?°C, protected from light and moisture |
| Intended Use | For laboratory research only |
Mechanism of Action
Dexlansoprazole is a proton pump inhibitor that irreversibly blocks the H?/K??ATPase enzyme in gastric parietal cells to suppress acid secretion. Its dual-delayed-release formulation ensures prolonged plasma exposure—achieving two peaks at ~1–2?h and 4–5?h post-dose—maintaining 24-hour acid inhibition.
Research Applications & Pharmacology
GERD & erosive esophagitis models: Extended acid suppression ideal for chronic and acute models
PK/PD studies: Especially relevant for freeze-dried form and dual-release dynamics
Formulation research: Useful in assessing stability, reconstitution, and particle behavior after freeze-drying
Drug-drug interaction assays: Known to involve CYP2C19 and CYP3A4 metabolism; investigate impact on co-administered drugs
Safety Profile & Handling
Preclinical tolerability: Generally well-tolerated; minimal systemic absorption with animal models
Handling: Use gloves and mask; reconstitute in sterile conditions; avoid aerosol use
Storage: Maintain at 2–8?°C in a dry, shaded environment
Disposal: Dispose according to institutional chemical waste protocols
Core Keywords
dexlansoprazole injection, dexlansoprazole freeze-dried, dexilant injection, dual delayed release PPI, CAS?138530-94-6, lab-grade PPI, acid suppression research
Research?Use Disclaimer
This product is intended solely for laboratory research use. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Improper use may pose health risks. Follow all institutional safety protocols.


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