Description

Ecnoglutide (also known as XW003) is a synthetic, long-acting, cAMP-biased glucagon-like peptide 1 (GLP-1) receptor agonist, identified by CAS number 2459531-73-6. It selectively induces cAMP accumulation over ?-arrestin recruitment, without inducing GLP-1R receptor internalization, in cell-based assays using human GLP-1R. In vivo studies have shown that Ecnoglutide reduces fasting and post-prandial blood glucose levels and decreases body weight and food intake in db/db mice. Synthesized under GMP conditions with a purity of ?98%, Ecnoglutide is ideal for research into obesity, type 2 diabetes, and metabolic disorders. Strictly for research use only.

Product Specifications

Mechanism of Action & Research Applications

Ecnoglutide functions as a cAMP-biased GLP-1 receptor agonist, selectively inducing cAMP accumulation over ?-arrestin recruitment. It does not induce GLP-1R receptor internalization in cell-based assays. In vivo, Ecnoglutide has demonstrated efficacy in reducing blood glucose levels and body weight in animal models. Its high purity and GMP manufacturing ensure reliability in experimental settings.

Disclaimer

This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Please adhere to institutional safety protocols when handling.